Efavir 200 Mg
- Manufacturer : Cipla Ltd
- Equivalent Brands : Sustiva
- Generic Brands : Efavirenz
Efavir 200mg Capsule is an antiviral medicine which is used in combination with other medicines to treat human immunodeficiency virus (HIV) infection. This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body. Close monitoring of liver function is necessary while receiving this medicine.
Efavir 200mg Capsule is an antiretroviral medication, used for HIV prevention and treatment. Efavir 200mg Capsule belongs to non-nucleoside reverse transcriptase inhibitors (NNRTIs) class of drugs. Efavir 200mg Capsule is prescribed to adults and children that are at least 3 months old.
Efavir 200mg Capsule prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Efavir 200mg Capsule is to be taken empty stomach.
Efavir 200mg Capsule (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV).
It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate.
Efavirenz in Efavir 200mg Capsule acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA.
This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus).
Efavir 200mg Capsule slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.
Efavir 200mg Capsule is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Efavir 200mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Efavir 200mg Capsule may be needed. Please consult your doctor.
Use of Efavir 200mg Capsule is not recommended in patients with moderate and severe liver disease.
Efavir 200mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Efavir 200mg Capsule may not be needed in these patients. Please consult your doctor.
Efavir 200mg Capsule may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Inform your doctor if you have a history of mental illness or convulsions (fits or seizures).
Ensure that efavirenz is always taken in combination with other anti-HIV medicines and never alone.
Seek immediate medical attention if you develop signs of dizziness, difficulty sleeping, drowsiness, difficulty concentrating or abnormal dreaming or any signs of skin rash or inflammation or infection.
Take the required precautions to prevent transmission as efavirenz does not prevent the spread of HIV virus to others through blood or sexual contact.
Do not drive if you have taken efavirenz as it may cause dizziness.
Do take if allergic to efavirenz or any of its ingredients.
Do not take if sufering with severe liver disease.
Avoid if patient is Pregnant or breastfeeding women.
Efavir 200mg Capsule is used in the treatment of HIV infection.
Store it at controlled room temperature (15- 25° C).