Gemita 200 Mg Injection
- Manufacturer : Fresenius Kabi India Pvt Ltd
- Equivalent Brands : Gemzar
- Generic Brands : Gemcitabine
Gemcitabine is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Gemcitabine is used to treat cancers of the pancreas, lung, ovary, and breast. Gemcitabine may also be used for purposes not listed in this medication guide.
Gemcitabine belongs to the class of drugs called anti-metabolites. The drug acts by interfering or blocking the DNA replication in the tumour cell. Thus, Gemcitabine prevents the proliferation and propagation of the cancer cells.
Gemcitabine can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches). Gemcitabine can affect your liver, kidneys, or lungs. Tell your doctor if you have stomach pain, dark urine, yellow skin or eyes, little or no urinating, swelling, rapid weight gain, severe shortness of breath, wheezing, or cough with foamy mucus. If you receive gemcitabine during or after radiation treatment, tell your doctor right away if you have severe skin redness, swelling, oozing, or peeling.
Liver injury - This medication could cause liver injury and causes death. The liver perform parameters have to be compelled to be assessed before beginning the treatment. The treatment ought to be interrupted if any signs and symptoms of liver injury seem.
Kidney injury - This medication could cause haemolytic pathology Syndrome (HUS) that may be a serious condition that causes fatalities. The urinary organ perform parameters have to be compelled to be assessed before beginning the treatment. The treatment ought to be interrupted if any signs and symptoms of urinary organ injury seem.
Lung toxicity - This medication could cause severe respiratory organ injuries like pneumonic pathology, pneumonic opening infiltrates. Any symptoms of respiratory issue and signs of respiratory organ impairment ought to learn to the doctor. The treatment ought to be interrupted if any symptoms seem.
Decrease in blood corpuscle count - This medication could lower the white blood corpuscle count (neutrophils) and platelets. shut observation of blood corpuscle count is critical. The baseline of the blood corpuscle count ought to be obtained before initiation of the treatment. don't begin the treatment if the counts area unit less.
Infections - the probabilities of occurring infections area unit additional in patients receiving this medication. Hold the therapy and begin with the broad-spectrum antibiotics if there area unit any signs and symptoms of fever. shut observation of the blood heat and therefore the blood corpuscle count is critical.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient’s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry. Do not receive a “live” vaccine while using gemcitabine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
Usual Adult Dose for Pancreatic Cancer:
Usual Adult Dose for Non-Small Cell Lung Cancer:
Usual Adult Dose for Breast Cancer:
Usual Adult Dose for Ovarian Cancer:
Gemcitabine is injected into a vein through an IV. A healthcare provider will give you this injection. Gemcitabine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. If any of this medicine accidentally gets on your skin, wash the area thoroughly with soap and warm water.
Store at below 25°C