In stock

  • Manufacturer : Cipla Ltd
  • Equivalent Brands : Duovir-N
  • Generic Brands : Lamivudine / Zidovudine / Nevirapine

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On Orders Over $249

Pack Size Price Qty Price Per Unit Addtocart
30 Capsules $39.00 $1.30
60 Capsules $57.00 $0.95
90 Capsules $83.00 $0.92
Duovir N is available to buy in increments of 1

1. Buy Duovir N Tablets Online

Duovir N Tablet is a nucleoside analogue. It is used in combination with other medications to treat HIV infection. It functions by interfering with the growth of the HIV infection.

On using this medication you may experience side effects such as nausea, joint pain, difficulty sleeping, diarrhea, cough, dizziness, swelling of the mouth, headache, reduced appetite, weakness, vomiting, darkening of the urine, numbness, mental/ mood disorders, ear pain, itchiness, sore throat and chest pain. If your reactions persist or worsen over time seek the help of your health care provider right away.

Before using this medication tell your doctor if; you are allergic to any ingredient contained within Duovir N Tablet, you are taking any other medications especially emtricitabine and zalcitabine, you have enlarged liver/ high levels of lactic acid/ abnormal liver functioning/ muscle problems/ kidney problems/ lactic acidosis/ nerve disorder/ pancreas problem, you are overweight, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage for this medication should be based on your medical history and current condition. The usual dose in adults for HIV infection is about 150 mg twice daily or 300 mg once daily.

2. How To Duovir N Work?

Lamivudine 150mg belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells). It does not cure HIV completely but reduces the chances of getting acquired immunodeficiency syndrome (AIDS) and HIV related infections or cancer.

Zidovudine 300mg belongs to a group of medications called nucleoside analogue reverse transcriptase inhibitors (NRTIs), also known as antiretrovirals. Zidovudine does not cure HIV infection; it reduces the amount of viruses in the body by inhibiting the enzyme (viral reverse transcriptase) which is essential for the virus to grow. Further, zidovudine also increases some white blood cells (CD4 cells) of the body that are important in fighting infections.

Nevirapine 200mg belongs to a class of anti-HIV medicines called non-nucleoside reverse transcriptase inhibitors (NNRTIs). Reverse transcriptase is an enzyme that HIV needs in order to multiply. Nevirapine stops reverse transcriptase from working, and thus helps control HIV-1 infection.

3. How To Take Duovir N Tablets?

You should take your Duovir-N tablets, 1 tablet twice daily, with a glass of water, with or without food. Since each tablet of Duovir-N contains half of the commonly prescribed daily doses of each of the 3 constituent drug, zidovudine, lamivudine and nevirapine, you should not need to change the dose of Duovir-N. You should continue to take your Duovir-N for as long as recommended by your doctor, and you will be monitored carefully to ensure that you do not develop any serious side effects, in which case your doctor will probably recommend that you stop taking your Duovir-N tablets.

4. Mechanism Action Of Duovir N?

Lamivudine and Zidovudine inhibits reverse transcriptase of HIV and prevents the proper transcription of the viral DNA. They both inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The chain elongation process is inhibited and finally the viral DNA growth is inhibited. The NNRTIs or Nevirapine attach to and block the HIV enzyme called reverse transcriptase.

5. Side Effects of Duovir N

In addition to its intended effect, Duovir N Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

  • Nausea
  • Diarrhea
  • Stuffy nose
  • Muscle pain
  • Unexplained weight loss
  • Joint pain
  • Vision changes
  • Skin rashes, hives and itching
  • Tiredness
  • Heat intolerance
  • Thyroid gland enlargement or goiter
  • Increased bruising or bleeding
  • Signs of pancreatitis

6. Warning of Duovir N Tablets

This drug will not keep you from spreading HIV to others so, take the necessary precautions

The serious effects of this drug mostly occur in women and obese people

Tell the doctor immediately if the liver problems worsens

Keep regular contact with your doctor in case of emergency

Patients should never miss the dose as it’s a part of combination therapy

7. Precaution of Duovir N Tablets

Consult your doctor if you have diabetes and are using insulin.

Patients receiving this therapy are always at a risk for infections and hence should report any such cases to the doctor.

Consult your doctor if you take any prescription medication; Inform your doctor if you take other medicine for treatment of HIV or hepatitis B infection, hairy cell leukemia [a type of blood cancer], or antibiotics for infection.

Lamivudine may rarely cause a serious side effect like lactic acidosis with symptoms such as pain or weakness of muscle, numbness or feeling cold in arms or legs, stomach pain, nausea, vomiting, lack of breath, aberrant heart rate, dizziness, weak or tired feeling; hence, inform the doctor immediately if you experience any of these symptoms.

It is possible to pass on HIV when on this medication and hence it is important to take necessary precautions to prevent HIV from spreading.

Inform you doctor if you notice signs of change in the distribution of fat (lipodystrophy), erosion of bones (osteronecrosis), or inflammation of pancreas (pancreatitis).

If you are on therapy it is important to use effective non hormonal method of contraception or condom so that a pregnancy can be avoided.

Use with caution in pediatric patients with a history of pancreatitis or other significant risk factors for pancreatitis.

8. Uses of Duovir N

Lamivudine 150mg indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection.

Zidovudine 300mg is used in combination with other antiretroviral (ART) medicines for the treatment of human immunodeficiency virus (HIV-1) infection. Zidovudine is also indicated for use in HIV-positive pregnant (over 14 weeks) women for prevention of maternal-fetal HIV transmission (passing of infection), and for primary preventive treatment of HIV infection in new-born infants.

Nevarapine 200mg is used to treat and control Human Immunodeficiency Virus (HIV-1) infection for adults, adolescents, and children of any age. It must be used along with other HIV medicines.

9. Storage of Duovir N

Duovir-N are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

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