Emeset 4 Mg
- Manufacturer : Cipla Ltd
- Equivalent Brands : Zofran
- Generic Brands : Ondansetron
Emeset 4mg Tablet is antiemetic drug used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. It works by blocking the action of a chemical substance that causes nausea and vomiting. The most common side effects are constipation and headache.
Emeset 4mg Tablet is an antiemetic (anti-nausea medicine). It inhibits the action of serotonin, a chemical messenger that can trigger nausea and vomiting.
Emeset 4mg Tablet belongs to the antiemetics drug group that is used for treating nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This medicine will block the chemical serotonin from releasing in your gut and your central nervous system. This will prevent vomiting and nausea.
Emeset 4mg Tablet is available in four different forms that can be taken orally; tablet, disintegrating (dissolving) tablet, solution and film. It also comes in an IV (intravenous) form that can be injected to your body by a doctor. You can take it with food or without food.
Emeset 4mg Tablet can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session. This medicine, belonging to the drug group named antiemetics, blocks serotonin, a natural substance present in the body that is known to cause vomiting.
Emeset 4mg Tablet is available both in tablet and liquid form. You can also take it in the IV form, when injected by a medical practitioner.
Your doctor must be informed if you are allergic to Emeset 4mg Tablet as well as other medications that block serotonin, along with any other allergies that you have. He/ She must also know about your medical history and if you had problems such as liver disease, irregular heartbeat and stomach or intestinal problems in the past.
Apart from that, you must also inform the doctor if you are under any medication for depression or any psychiatric disorder.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Emeset 4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Emeset 4mg tablets contains ondansetron, a potent and highly selective 5HT3 receptor-antagonist that is used as an antiemetic to control the nausea and vomiting associated with cancer chemotherapy and radiotherapy, also to prevent post-operative nausea and vomiting.
It is thought that chemotherapy, radiotherapy and surgery can cause the release of serotonin (5HT) from the cells of the small intestine, which stimulates 5HT3 receptors that are found on the vagal nerves in the intestines. Stimulation of these nerve endings by serotonin sends nerve messages to the vomiting centre in the brain (a complex area of neuronal networks) that induces the vomiting reflex.
Ondansetron is thought to work by blocking the transmission of nerve messages from the intestines to the vomiting centre in the brain. There are also 5HT3 receptors in the chemoreceptor trigger zone (CTZ) of the area postrema in the brain, which is where the vomiting reflex originates, by sending nerve messages to the vomiting centre.
It is thought that ondansetron in Emeset 4mg also blocks the 5HT3 receptors in the CTZ and this also prevents activation of the vomiting centre in the brain. Ondansetron in Emeset 4 thereby blocks the 5HT3 receptors found in the peripheral nervous system in the intestine and the central nervous system in the brain.
This dual effect of ondansetron in Emeset 4mg prevents vomiting caused by chemotherapy and radiotherapy; also post-surgery vomiting and also helps relieve the feelings of nausea.
are allergic to ondansetron or any other selective 5HT3 receptor antagonists or any ingredients in Emeset 4
are pregnant or are breastfeeding
have liver disease
have subacute intestinal obstruction (constipation)
are taking medicines that interact with Emeset 4mg, including: the anticonvulsants phenytoin and carbamazepine, the antibiotic rifampicin, the analgesic tramadol
Take Emeset 4mg 30 minutes before your food.
If you vomit within 30 minutes after taking the Emeset 4mg, take the same amount again. If vomiting continues, check with your doctor.
If Emeset is used for a short duration, for e.g. 6 -10 days, the risk of side-effects is minimal (well-tolerated).
You can use oral disintegrating film/strip (medicated strip that dissolves when comes in contact with a wet surface) form of the Emeset if you are nauseous to swallow a tablet or capsule.
If you are using Emeset 4mg in the form of oral disintegrating film/strip:
Emeset 4mg Tablet is used in the treatment and prevention of nausea and vomiting.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.