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What Is Mupirocin

what is mupirocin

Description

Mupirocin (2 percent) ointment is a unique topical agent recently developed for use in the treatment of superficial skin infections. It has shown excellent in vitro and in vivo activity against gram-positive staphylococci and streptococci, which are the predominant pathogens in most superficial skin infections, and against gram-negative Hemophilus influenzae and Neisseria gonorrhoeae.

 At present, mupirocin (2 percent) ointment has been approved for use in the treatment of impetigo, but an analysis of several recent clinical trials has also indicated the potential for mupirocin treatment of other primary and secondary skin infections.

How to use Mupirocin Ointment

Read the Patient Information Leaflet if available from your pharmacist before you start using mupirocin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication only on the skin. Clean and dry the affected area first. Then apply a small amount of ointment to the area as directed by your doctor, usually 3 times a day. You may cover the treated area with a bandage.

Use this medication regularly to get the most benefit from it. Continue to use it for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Avoid using this medication around your eyes, nose, mouth, or on large areas of damaged or broken skin unless otherwise directed by your doctor. If you accidentally get it in your eyes, nose, or mouth, rinse well with plenty of water.

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Although uncommon, mild burning or stinging after using this medication may occur. If you have severe burning, stinging, or irritation, stop using this medication and tell your doctor right away.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Precautions

Before using mupirocin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as polyethylene glycol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease (if you are using a brand of mupirocin that contains polyethylene glycol).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

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