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What Is Hydroxyurea

what is hydroxyurea

what is hydroxyurea

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

skin numbness or purple discoloration, skin ulcers or open sores;

painful or difficult urination;

numbness, tingling, or burning pain in your hands or feet;

signs of a weak immune system--fever, chills, body aches, flu symptoms, sores in your mouth and throat, pale skin, feeling light-headed or short of breath, easy bruising or bleeding;

side effects can this medication cause?

Hydroxyurea may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • vomiting
  • diarrhea
  • loss of appetite
  • weight gain
  • sores in the mouth and throat
  • constipation
  • rash
  • pale skin
  • dizziness
  • headache
  • hair loss
  • changes in skin and nails


See also Warning section.

Before taking hydroxyurea, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, blood/bone marrow disorders (such as bone marrow suppression, neutropenia, thrombocytopenia, anemia), HIV infection, high uric acid level in the blood, radiation treatment.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.


Hydroxyurea comes as a capsule to take by mouth. Your dose will be based on your weight, medical condition, and response to treatment.The medicine is usually taken once a day.When hydroxyurea is used to treat certain types of cancer, it's sometimes taken once every three days.Try to take the drug around the same time each day.Don't crush, chew, or split the capsules. Swallow them whole.Wear latex or rubber gloves when you handle hydroxyurea capsules to protect your skin.Wash your hands right after you touch the bottle of medicine.Follow the instructions on your prescription label carefully when taking this medicine. Don't take more or less hydroxyurea than is recommended.


Symptoms of a hydroxyurea overdose may include:

Pain, redness, swelling, or scaling on the hands and feet

Sores in the mouth and throat

Darkening of the skin

If you suspect an overdose, contact a poison control center or emergency room immediately.

You can get in touch with a poison control center at 800-222-1222.

Missed Dose of Hydroxyurea

If you miss a dose of hydroxyurea, take it as soon as you remember.

But skip the missed dose if it's almost time for your next scheduled dose.

Don't take extra medicine to make up for a missed dose.

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