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What Is Glipizide

what is glipizide

What is glipizide?

Glipizide is a prescription drug. It comes as an oral immediate-release tablet and oral extended-release tablet. Glipizide oral tablet is available as the brand-name drugs Glucotrol and Glucotrol XL. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand.

Glipizide and Metformin combination is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. Normally, after you eat, your pancreas releases insulin to help your body store excess sugar for later use.

Glipizide Dosage

Glipizide comes as a tablet in regular and an extended-release form.Your doctor may start you on a low dose of glipizide and gradually increase it.The regular tablet is typically taken one or more times a day by mouth, about 30 minutes before meals.The extended-release tablet is usually taken by mouth once a day before breakfast.Swallow the extended-release tablets whole. Don't chew, crush, or divide them.

Interaction

Many drugs can affect your blood sugar, making it harder to control. Before you start, stop, or change any medication, talk with your doctor or pharmacist about how the medication may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of high or low blood sugar. (See also Side Effects section.) Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Beta-blocker medications (including metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients that could affect your blood sugar. Ask your pharmacist about using those products safely.

Side effects

  • Dark urine
  • Light-colored stools
  • Yellowing of the eyes or skin
  • Mental or mood changes
  • Fever
  • Sore throat
  • Dizziness
  • Jittery feelings
  • Red or itchy skin
  • Rash, hives, or blisters
  • Uncontrollable shaking

Glipizide Warnings

You shouldn't take glipizide if you have type 1 diabetes (the body doesn't produce any insulin) or diabetic ketoacidosis (a dangerous condition that can occur if high blood sugar is untreated).

Before taking this medicine, tell your doctor if you have or have ever had:

  • G6PD deficiency (an inherited enzyme condition)
  • Hormone disorders involving the pituitary, adrenal, or thyroid gland
  • Heart, kidney, or liver disease
  • Short-bowel syndrome (part of the intestine is removed or missing)
  • Narrowing or a blockage of the intestines
  • Ongoing diarrhea

Precautions

Before taking glipizide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, thyroid disease, certain hormonal conditions (adrenal/pituitary insufficiency, syndrome of inappropriate secretion of antidiuretic hormone-SIADH), electrolyte imbalance (hyponatremia).

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

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