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What Is Boniva

What Is Boniva

What Is Boniva

 Boniva (ibandronate) is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

 Boniva is prescription medicine used to treat or prevent osteoporosis in women after menopause. Ibandronate helps increase bone mass and helps reduce the chance of having a spinal fracture.

 It is not known how long Boniva works for the treatment and prevention of osteoporosis. You should see your doctor regularly to determine if this medicine is still right for you.

 Boniva is the brand name of the medicine ibandronate, which is used to prevent and a condition in which bones become weak and break easily — in women who've been through menopause.The Food and Drug Administration (FDA) approved Boniva in 2003. It's marketed by Genentech, Inc.

 What are the possible side effects of ibandronate (Boniva)?

 Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

 Stop using ibandronate and call your doctor at once if you have:

  • chest pain, new or worsening heartburn;
  • difficulty or pain when swallowing;
  • pain or burning under the ribs or in the back;
  • severe heartburn, burning pain in your upper stomach, or coughing up blood;
  • new or unusual pain in your thigh or hip;
  • jaw pain, numbness, or swelling;
  • severe joint, bone, or muscle pain; or
  • low calcium levels--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).


 Take at least 60 minutes before first food, drink or other medications; take with full glass of water, in upright position & remain upright for 60 minutes to minimize esophageal adverse eventsTake with plain water only; juice or coffee can significantly reduce bioavailabilityDo NOT chew or suck tablet

What is the dosage for Boniva?

  • The dose of ibandronate is 150 mg orally once monthly.
  • The tablet should be taken on the same day of each month.
  • Tablets should be taken at least 60 minutes before the first food or drink of the day (other than plain water) or before other oral medication, because of concern that that food or medication will interfere with the absorption of ibandronate. Absorption of ibandronate from the intestine is poor, and any potential further decrease in absorption by food or medications needs to be avoided.
  • Ibandronate tablets also should be swallowed whole with six to eight ounces of plain water while in an upright position, in order to be certain that the tablets enter the stomach. If the tablets stick in the esophagus they can irritate the esophagus. For the same reason, patients should not lie down for 60 minutes after taking ibandronate since tablets are more likely to stick in the esophagus when lying down.
  • Tablets should not be chewed or sucked in order to avoid irritation of the mouth and throat.
  • The dose of ibandronate administered intravenously is 3 mg administered over 15-30 seconds every three months.

Which drugs or supplements interact with boniva?

antacids, and other products that contain aluminum, magnesium, or iron may reduce absorption of ibandronate. Ibandronate should be administered at least 60 minutes before administration of any oral medication, including medications containing iron, aluminum, magnesium, or calcium.Patients should wait at least 60 minutes after taking ibandronate before taking other oral medications.

Is boniva safe to take if I'm pregnant or breastfeeding?

Bisphosphonates have been shown to cause fetal harm in animals, but there are no data on risk to the fetus in humans. Ibandronate should be used during only if the physician feels that its potential benefit justifies the potential risk to the fetus.

Ibandronate is secreted into the breast milk of animals. It is not known whether it is secreted into human breast milk. Since most medications do appear in human breast milk, it is generally recommended that caution be exercised when ibandronate is given to women.

What else should I know about boniva?

What preparations of ibandronate are available?

  • Tablets: 150 mg
  • Intravenous injection: 3 mg/3 ml

How should I keep ibandronate stored?

Ibandronate tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

Boniva Overdose

Symptoms of a Boniva overdose may include:

  • Nausea
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Muscle cramps
  • Tight muscles in your face
  • Seizures
  • Unusual thoughts or behaviors

If you suspect an overdose, drink a full glass of milk and contact a poison control center or emergency room immediately.You can get in touch with a poison control center at 800-222-1222.

Missed Dose of Boniva

If you forget to take a daily 2.5 mg tablet of Boniva, skip your missed dose and continue on your regular medication schedule the following morning.If you forget to take a monthly 150 mg tablet of Boniva, take it the morning after you remember if your next scheduled dose is more than seven days away.If your next scheduled dose is seven or fewer days away, skip the missed dose and wait for your next scheduled dose. Don't take two 150 mg tablets in one week.Call your doctor if you miss a Boniva injection.

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