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What Is Anastrozole Used For

what is anastrozole used for

About Anastrozole

Anastrozole falls under a category of drugs known as aromatase inhibitor. It is used to treat breast cancer in post-menopausal women. It functions by lowering the estradiol concentrations in the blood which slows down the tumor growth and size.

On using Anastrozole you may experience side effects such as muscle pain, breast pain, diarrhoea, constipation, cough, dizziness, flu-like symptoms, stomach pain, vomiting, difficulty with sleeping, weakness, rapid weight gain, reduced appetite, hives, headache, skin rash, numbness, irregular heartbeat, clouded thoughts, fever, chills, skin ulcers and swelling. Notify your doctor promptly should any of the allergic reaction show and worsen over time.

Who should NOT take this medication?

Do not use anastrozole if you:

  • are allergic to anastrozole or any ingredients of the medication
  • are allergic to any other aromatase inhibitor medications (e.g., letrozole, exemestane)
  • are breast-feeding
  • are pregnant

What is anastrozole-oral, and how does it work (mechanism of action)?

Anastrozole is an aromatase inhibitor, an anti-cancer medication use for the adjuvant or initial treatment of breast cancer in post-menopausal women. Estrogen causes or increases growth of certain breast cancers. Anastrozole works by blocking aromatase enzyme, which is involved in estrogen production in the body. This leads to decreased tumor size or delayed progression of tumor growth in some women. The FDA approved brand name anastrozole (Arimidex) in 1995.

Serious side effects

  • Hot flushes
  • Feeling weak or a lack of energy
  • Feeling sleepy
  • Joint pain or stiffness
  • Vaginal dryness
  • Vaginal bleeding
  • Thinning of hair (hair loss)
  • Mild skin rash
  • Feeling sick (nausea)
  • Diarrhoea
  • Headache
  • Loss of appetite (anorexia)

Which drugs or supplements interact with anastrozole-oral?

Anastrozole should not be used with tamoxifen because tamoxifen can reduce anastrozole levels in the body and decrease its therapeutic effects.

Estrogens decrease the effect of anastrozole by increasing estrogen levels in the body.

Is anastrozole-oral safe to take if I'm pregnant or breastfeeding?

Anastrozole is not recommended for pregnant mothers under any circumstances. Anastrozole may cause fetal harm and terminate pregnancy.

It is not known whether anastrozole enters breast milk. It should not be administered to nursing mothers to avoid any harm to the newborn.

How should I keep anastrozole-oral stored?

Store anastrozole tablets at room temperature, between 20 C – 25 C (68 F – 77 F).

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