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What is vesicare?

vesicare (solifenacin) reduces muscle spasms of the bladder and urinary tract.

vesicare is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

vesicare may also be used for purposes not listed in this medication guide.


Solifenacin is used to treat an overactive bladder. By relaxing the muscles in the bladder, solifenacin improves your ability to control your urination. It helps to reduce leaking of urine, feelings of needing to urinate right away, and frequent trips to the bathroom. This medication belongs to the class of drugs known as antispasmodics.

How should I take vesicare?

Take Vesicare exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Vesicare is usually taken once per day with or without food. Follow your doctor's instructions.

Take this medicine with water.

Do not crush, chew, or break the tablet. Swallow it whole.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time the next day and stay on your once-daily schedule. Do not take extra medicine to make up the missed dose.

Do not take 2 doses on the same day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Vesicare?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Solifenacin can decrease perspiration and you may be more prone to heat stroke.

This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

vesicare Side Effects

Common Side Effects of VESIcare:

  • Dry mouth
  • Constipation
  • Urinary tract infection
  • Blurred vision
  • Heat exhaustion or heat stroke (due to decreased perspiration)
  • Bladder pain
  • Bloody or cloudy urine
  • Chills
  • Decrease in urine frequency or volume
  • Difficult, painful, or burning sensations during urination
  • Difficulty passing urine
  • Fatigue (severe)
  • Fever
  • Frequent urge to urinate
  • Swelling in the lower legs

Important warnings

Other conditions warning: You shouldn’t take this drug if you have urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. Use this drug with caution if you have the heart problem called QT prolongation (irregular heart rate).

Swelling (angioedema) warning: In rare cases, this drug may cause swelling of your face, lips, tongue, or throat. If swelling occurs and makes it hard for you to breathe, call 911 or go to the emergency room right away.

Dementia warning: Research has indicated that this type of medication can cause effects similar to those caused by drugs called anticholinergics. This can raise your risk of dementia.