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What is Ubiquinone?

Ubiquinones are a class of fat-soluble benzoquinones that are involved in the body's mitochondrial electron transport. They are found in most organisms, from bacteria to mammals, hence the name "ubiquinone" ("ubiquitous or widespread quinone").

What is it used for?

  • Traditional/ethnobotanical:The first ubiquinone was isolated in 1957. Since that time, ubiquinones have been extensively studied in Japan, Russia, and Europe with research in the US beginning more recently. Popular press accounts claim that roughly 12 million Japanese use ubiquinones as the medication of choice for management of cardiovascular diseases, with more than 250 commercially available preparations. Ubiquinone is touted as an effective treatment of congestive heart failure (CHF), heart rhythm irregularities, high blood pressure, and in reducing injury to the heart muscle caused by lack of oxygen. Other claims include increasing exercise tolerance, stimulating the immune system, and counteracting the aging process. Ubiquinone has not been approved for therapeutic use in the US, but it is available as a food supplement.
  • General uses:Ubiquinone may have applications in heart disease, especially CHF, although there is a lack of consensus. Studies in neurological disorders are less promising. Limited clinical trials have been conducted to support its widespread use for other conditions.

How to take?

Although no formal recommendations exist from professional organizations for CoQ10 supplementation, most physicians recommend 100-400 mg/day.

Side Effect

Common side effects may include:

  • upset stomach, nausea, vomiting, loss of appetite;
  • diarrhea;
  • skin rash; or
  • low blood pressure.


When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.If you choose to use ubiquinone, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.To take the disintegrating tablet, use dry hands to remove the tablet from the package, and place it in your mouth. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.