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Trimix Erectile Dysfunction

Trimix Erectile Dysfunction


Tri-Mix is indicated in the treatment of erectile dysfunction in males. Tri-Mix contains three drugs from complimentary classes designed to act synergistically, mixed into a sterile injection.

How is it best taken?

Ideally, the injection should be administered just prior to foreplay. It is administered via intravavernosal injection and should produce an erection in 5 to 20 minutes and can be expected to last up to one hour. To prevent bruising, apply firm pressure to the injection site for 5 minutes after injecting. Do not use Tri-mix Injection more than two times a week; use at least 24 hours apart. There is a possibility of needle breakage with use of Tri-mix Injection: you should pay careful attention to your doctor's instructions and handle syringe and needle properly. If the needle breaks during injection, you should promptly contact your doctor.

How Does It Work?

TriMix is an easy-to-use, self-injected penile injection medication. When injected into the penis, TriMix’s blend of three vasodilators causes the corpus cavernosum to relax, expand and fill with blood. With TriMix, you’ll experience longer and fuller erections in just 5 minutes or less and can even last even through climax.

TriMix Benefits

  • Safe and reliable
  • Fast-acting and long-lasting erections
  • Affordable compared to oral medications
  • Not affected by alcohol consumption

Storing your medication

The alprostadil in Trimix can weaken over time, so Trimix should be stored in the refrigerator and away from light. This can keep the medication good for a few additional months. If you’re using Bimix or papaverine, you don’t need to keep the medication in your refrigerator because these medications don’t contain alprostadil.

Don’t use the medication if:

  • It has particles or is cloudy.
  • The rubber stopper comes off of the vial.

After your second training visit, your medication will be delivered directly to your home from the compounding pharmacy (specialized pharmacy). Call the compounding pharmacy to make arrangements for billing and shipping. This will limit delays in delivery.

Call your APP when you need a new prescription.

Make Sure You Inject Trimix Correctly

Most common cause of Trimix not working is that it is not injected correctly. Most common error occurs when Trimix is injected into or just under the skin instead of corpus cavernosum.  Proper education, which we provide to all our patients, is crucial to success.

Depending on the type of Trimix used, refrigeratable or non-refrigeratable, Trimix can also lose potency over time if it is exposed to room temperature for prolonged periods of time. In this situation, a fresh Trimix bottle should be used.  We usually prescribe Trimix in a small volume (5 ml per bottle) so that men can thaw a fresh bottle each month or so.

Trimix from Different Pharmacies is Not Interchangeable

Because Trimix is a custom prepared compounded medication, different pharmacies make it in different concentrations and proportions.  Usually, preparations from different pharmacies are not interchangeable.  When a new pharmacy is used, test dosing in our offices is performed to determine the correct dose.

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