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Topiramate Weight Loss Dosage

Topiramate Weight Loss Dosage

What Is Topamax (Topiramate)?

While its exact mechanism of action is unknown, studies suggest Topamax might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves. Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire.


Drug information provided by: Micromedex

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.Take this medicine once a day in the morning, with or without food. Avoid taking this medicine in the evening to prevent trouble sleeping.


Topamax can lead to serious eye problems that, if left untreated, could cause permanent vision loss. These include a sudden decrease in vision that may be accompanied by eye pain and redness, as well as a blockage of fluid in the eye resulting in secondary angle closure glaucoma.Topamax might decrease sweating and increase your body temperature resulting in a fever. Some people may need to be hospitalized if this occurs.

Topamax & Weight Loss

Regardless of how the drug works, it is known that it is often used as an off-label pill to lose weight. Although not everyone will lose weight from taking Topamax, many people lose a significant amount throughout their treatment. It is also important to mention that although it isn’t approved as a standalone drug for weight loss, it is included in the formulation known as “Qsymia” which is approved specifically for weight loss.

Side Effects

  • Mood changes such as aggression, agitation, apathy, and depression
  • Loss of appetite
  • Weight loss
  • Stomach pain
  • Fever, chills or sore throat
  • Reduced sensation or perception
  • Red, irritated, or bleeding gums

Rare side effects:

  • Blood in urine
  • Frequent, difficult or painful urination
  • Loss of bladder control
  • A decrease in sexual performance/desire
  • Ringing or buzzing in the ears
  • Hearing loss
  • Skin rashes
  • Itching
  • Swelling
  • Trouble breathing
  • Nosebleeds
  • Pale skin
  • Red or irritated eyes
  • Lower back or side pain


It is known that this drug tends to help people lose weight, and there is a relationship between weight loss and the dosage taken. Those that take higher doses, tend to lose more weight than those on lesser doses. It should be speculated that dose in relationship to bodyweight as well as tolerance may also play a role. For a smaller statured individual, less of a dose may produce more weight gain than the same dose in a larger person.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
  • Keep out of the reach of children.
  • Do not keep outdated medicine or medicine no longer needed.
  • Ask your healthcare professional how you should dispose of any medicine you do not use.

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