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Topiramate High

Topiramate High

What Is Topamax (Topiramate)?

Topamax is the generic form of the drug topiramate. Topiramate medications were designed as antiepileptic and anticonvulsive agents to treat seizures in people with epilepsy. Since the drug became available, it has been used to treat migraines and help people recover from alcoholism and drug addiction. The effectiveness of Topamax in treating drug addiction is still being researched. Recently, Topamax has been prescribed to people with bipolar disorder and especially people with the co-occurring bipolar disorder and drug addiction. Topamax is said to help stop cravings, stabilize mood, and help prolong abstinence from drug or alcohol use. Topamax is also often used in rehabilitation centers, to help prevent seizures and convulsions in people undergoing drug and alcohol detoxification.

How Is Topamax (Topiramate) Used?

Topamax should be used exactly as prescribed by your medical provider. For ongoing treatment, such as migraine or seizure prevention, Topamax is typically prescribed to take twice daily. If you are receiving Topamax to help prevent detoxification seizures or to treat alcoholism or bipolar disorder, your dosage may vary. When taking topiramate, always follow your doctors’ specific instruction as they relate to you. Do not take Topamax with other drugs and be sure to consult with a medical provider if you are on any other prescription medications.


Topamax is available in tablets (25 milligrams (mg), 50 mg, 100 mg, and 200 mg), extended release oral capsules (25 mg, 50 mg, 100 mg, 150 mg, 200 mg), and sprinkle capsule (15 mg and 25 mg) that can be taken orally or sprinkled onto soft food.Those who take Topamax typically start with a low dose of 25 or 50 mg per day (divided over two doses), increasing it slowly by 25 to 50 mg per week until an effective daily dose is reached.In the case of adults and children 10 years or older, the dose may be increased by 100 mg in week five and six if Topamax is used by itself. The final recommended adult dose is 400 mg, taken in two divided doses daily.

Topamax Overdose

If you think you have taken too much Topamax, call 911 or contact your doctor immediately. Signs of an overdose may include:

  • Decreased awareness or responsiveness
  • Severe or unusual sleepiness/drowsiness
  • Dullness
  • Tiredness
  • Weakness or feeling sluggish

Missed Dose of Topamax

If you miss a dose, take it as soon as you remember. However, if you are within six hours of your next dose, skip the missed dose and continue with your regular schedule.

Side Effect

  • High blood ammonia levels. High ammonia in the blood can affect your mental activities, slow your alertness, make you feel tired, or cause vomiting. This has happened when topiramate is taken with a medicine called valproic acid (Depakene and Depakote).
  • Low body temperature. Taking topiramate when you are also taking valproic acid can cause a drop in body temperature to less than 95°F, feeling tired, confusion, or coma.
  • Kidney stones. Drink plenty of fluids when taking topiramate to decrease your chances of getting kidney stones.
  • Effects on thinking and alertness. Topiramate may affect how you think and cause confusion, problems with concentration, attention, memory, or speech. Topiramate may cause depression or mood problems, tiredness, and sleepiness.
  • Dizziness or loss of muscle coordination.


If you’re struggling with alcoholism or drug addiction, you may want to take certain precautions before participating in a Topamax drug trial as the drug tends to interact with a wide range of medications and physical conditions. Whether you’re taking prescription or nonprescription drugs, such as vitamins or nutritional supplements, Topamax’s effects on brain chemistry can affect how the body reacts to other drugs.

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