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Topiramate For Anxiety

Topiramate For Anxiety


Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), have been associated with significant weight gain, a problem that frequently leads to noncompliance and premature discontinuation of treatment. Topiramate is a novel anticonvulsant that has also been used as a mood stabilizer and augmentation agent in mood disorders. Topiramate has been observed to have an interesting side effect of weight loss in some individuals. In this study, topiramate was added to the treatment regimen of patients with a primary DSM-IV anxiety disorder who had experienced substantial SSRI-induced weight gain, in an attempt to induce weight loss.

What is topiramate for anxiety?

topiramate for anxietyis often sold under the brand name Topamax. It is an anti-convulsive drug that stands apart from all other drugs used to treat convulsions or mood disorders because it does not share the same chemical composition. Medical researchers currently do not know how Topiramate works.

Is it safe for children and teens to take topiramate for anxiety?

Yes, the FDA has approved the drug for children.

side effect

  • Somnolence
  • Dizziness
  • Vision problems
  • Unsteadiness
  • Speech problems
  • Psychomotor slowing
  • Pins and needles
  • Nervousness
  • Nausea
  • Memory problems
  • Tremor
  • Confusion


Using this medicine could increase the level of acid in your blood, causing metabolic acidosis. Symptoms may include loss of appetite, feeling tired, changes in your heartbeat, or having problems thinking clearly.If metabolic acidosis is not treated, it could cause brittle or soft bones leading to osteoporosis or other conditions. It might also result in kidney stones or slow the rate of growth in children.

Drug Interactions

Before starting Topamax, be sure to give your physician a list of all the drugs you are using, including prescription, over-the-counter (OTC), vitamins, herbal supplements, and recreational drugs.Using carbamazepine (Tegretol) or phenytoin (Dilantin) may increase the elimination of Topamax from your body, making it less effective.The following drugs might increase your risk of kidney stones and metabolic acidosis:

  • Acetazolamide (Diamox)
  • Dorzolamide (Trusopt)
  • Methazolamide (Neptazane)
  • Dichlorphenamide (Daranide)


Children should start with up to 25 mg taken each night for the first week, with the dose being increased at 1 or 2 week intervals. The maximum maintenance dose is based on weight.Migraine patients are usually given 25 mg every night for the first week, with the dose being increased by 25 mg weekly. The maximum dose is 100 mg, to be taken in two divided doses.

Dose of Topamax

If you miss a dose, take it as soon as you remember. However, if you are within six hours of your next dose, skip the missed dose and continue with your regular schedule. Never take extra to catch up. If you forget more than one dose, contact your doctor.

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