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Tiotropium Bromide/Formoterol

Tiotropium Bromide/Formoterol

Tiotropium Bromide/Formoterol

Information about drug Tiotropium Bromide combination includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. To view the price of the drug, click on the brand name. The generic Tiotropium Bromide combination is manufactured by 3 companies. Medindia's drug directory has currently 9 Brands of Tiotropium Bromide listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies.

What is Tiotropium Bromide/Formoterol used for?

Duova inhaler is a combination treatment used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), which is a progressive obstructive airways disease that usually gets worse with time. The symptoms of COPD are caused by bronchospasm and are similar to asthma, including tightness of the chest, wheezing and shortness of breath, as well as chronic cough with sputum production because the lung tissues have become damaged. Duova Inhaler provides improved action to open airways and improve breathing, which helps relieve symptoms, where a single medication has not been sufficiently effective.

How does Tiotropium Bromide/Formoterol work?

Duova Inhaler contains two bronchodlators that are used for long-term treatment of chronic obstructive pulmonary disease (COPD). Formoterol in Duova Inhaler is a potent, selective, long-acting beta-agonist that acts locally in the lungs and works as a bronchodilator by relaxing the smooth muscle in the airway walls to widen the airways. Tiotropium in Duova Inhaler is a long-acting anticholinergic that acts on specific receptors

What does Tiotropium Bromide/Formoterol ?

Duova Inhaler is a metered dose inhaler containing a combination of two active ingredients; formoterol fumarate dihydrate (9mcg), a long-acting beta-agonist, and tiotropium bromide monohydrate (6mcg) a long-acting anticholinergic used to treat chronic obstructive pulmonary disease (COPD). Each dose delivers an inhalation aerosol containing 9mcg formoterol and 6mcg tiotropium. Each inhalation canister contains 200 doses.

Warnings and Precautions

Since DUOVA Inhaler contains a combination of tiotropium and formoterol, the warnings and precautions for both drugs should be observed.

DUOVA Inhaler is intended as a once-daily maintenance treatment for COPD and is not indicated for the initial treatment of acute episodes of bronchospasm, i.e. rescue therapy. In the event of an acute attack, a rapid-acting beta2-agonist should be used.


 Consistent with its anticholinergic activity, tiotropium bromide should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia or bladder-neck obstruction (e.g., difficulty passing urine, painful urination), urinary retention or prostatic hyperplasia. Prescribers and patients should be alert for signs and symptoms of prostatic hyperplasia. Patients should consult a physician immediately should any of these signs or symptoms develop.

side effects

The most commonly reported side effects when taking Duova Inhaler include: dry mouth and throat, cough, rapid heartbeat (tachycardia), blurred vision, high pressure in the eye (glaucoma), oral candida (thrush), dizziness, nausea, constipation, upset stomach, stuffy nose, dysphonia (hoarse voice), sinusitis, viral Infection, bronchitis, chest pain, tremors, dizziness, insomnia, tonsillitis, rash. Paradoxical bronchospasm is uncommon but can occur in which your inhaler worsens your breathing. Also hypokalaemia (low blood potassium) is an uncommon but serious side effect.


Before using tiotropium, tell your doctor or pharmacist if you are allergic to it; or to ipratropium; or to atropine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.


If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

If you are using this medication to treat asthma, learn to use a peak flow meter, use it daily, and promptly report worsening breathing problems (such as readings in the yellow/red range, increased use of quick-relief inhalers).

Because the flu virus can worsen breathing problems, ask your doctor or pharmacist if you should have a flu shot every year.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not freeze. Do not store in the bathroom. The inhaler should be thrown away when it becomes locked (which means that all the medication is used up) or 3 months after putting the cartridge in the inhaler, even if there is medication left in the cartridge. Keep all medications away from children and pets.