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Tinidazole Ofloxacin

Tinidazole Ofloxacin

Tinidazole Ofloxacin

Tinidazole is an antibiotic that is used to treat certain types of vaginal infections (bacterial vaginosis, trichomoniasis). It is also used to treat certain types of parasite infections (giardiasis, amebiasis). It works by stopping the growth of certain bacteria and parasites.

 This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

How ofloxacin + tinidazole works

This is a combination of two antibiotics: Ofloxacin and Tinidazole.Ofloxacin works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Tinidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

How to use Tinidazole

Take this medication by mouth as directed by your doctor, usually once daily. To prevent stomach upset, take this medication with food. The dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight.

 For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

 Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a short time. Stopping the medication too early may result in a return of the infection.

How should this medicine be used?

Tinidazole comes as a suspension (liquid) prepared by the pharmacist and a tablet to take by mouth. It is usually taken with food as a single dose or once a day for 3 to 5 days. To help you remember to take tinidazole (if you are to take it for more than one day), take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tinidazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Precautions

Epilepsy or other predisposing seizures; known or suspected CNS disorders; renal impairment; myasthaenia gravis, superinfection; children < 18 years; exposure to strong sunlight & UV light. Avoid alcohol.

Interactions

Ofloxacin: Probenecid decreases elimination. Antacids containing Mg & aluminium, sucralfate reduce absorption.

Tinidazole: Synergism with ampicillin, doxycycline & co- trimoxazole.

Ofloxacin: Corticoteriods may increase risk of tendon repture. Increases effects of oral anticoagulants. Increased risk of seizures with NSAIDs.

Tinidazole: Disulfiram- like reaction with alcohol.

Side-effects

The following is a list of possible side-effects that may occur in medicines that contain Ofloxacin / Tinidazole. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

  • Headache
  • Diarrhea
  • Photosensitivity
  • Nausea
  • Hallucination
  • Sinus tachycardia
  • Insomnia
  • Seizures
  • Dizziness
  • Vomiting
  • Ofloxacin

Drug Interactions of Ofloxacin 200mg + Tinidazole 600mg:

Probenecid Decreases Elimination. Antacids May Reduce Ofloxacin Absorption, Avoid For 2 Hr Either Side Of Administration. Cimetidine May Increase Ofloxacin Concentrations. Monitor Blood Glucose In Patients On Antidiabetic Medication. Potentially Fatal: Corticosteroids May Increase Risk Of Tendon Rupture. Increases Effects Of Oral Anticoagulants, Ciclosporin, Theophylline. Increased Risk Of Seizures With NSAIDs. Avoid In Patients Taking QT Prolonging Medication (E.G. Class Ia Or III Antiarrythmics, Astemizole, Terfenadine, Cisapride, Erythromycin, Pentamidine, Phenothiazines And Some TCA).S

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

 Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised October 2017. Copyright(c) 2017 First Databank, Inc.

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