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Tenofovir + Emtricitabine

Tenofovir + Emtricitabine

Tenofovir + Emtricitabine

Truvada is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the following uses:

 To treat HIV infection in adults and children who weigh at least 37 pounds (17 kilograms). Truvada for HIV treatment is always used in combination with other HIV medicines. HIV medicines can’t cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV treatment regimen) every day helps people with HIV live longer, healthier lives and also reduces the risk of HIV transmission. 

 What should I tell my health care provider before taking Truvada?

Before taking Truvada, tell your health care provider:

  • If you are allergic to either of the HIV medicines in Truvada (emtricitabine or tenofovir disoproxil fumarate) or any other medicines.
  • If you have liver problems, including HBV.
  • If you have kidney problems or receive kidney dialysis treatment.
  • If you have bone problems.
  • If you have any other medical conditions.
  • If you are pregnant or plan to become pregnant. Whether Truvada can harm an unborn baby is unknown. Talk to your health care provider about possible risks with taking Truvada when pregnant. If you become pregnant while taking PrEP, talk to your health care provider about whether to continue taking Truvada.


This product is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. This product is a combination of two different drugs: emtricitabine and tenofovir. Emtricitabine is called a nucleoside reverse transcriptase inhibitor, while tenofovir is called a nucleotide reverse transcriptase inhibitor. They are often called NRTIs.

This product should not be used by itself to help control HIV infection. Doing so can make your treatment less effective. Combination treatment with at least one other HIV medication should be used.

taking this medicine

You should not take emtricitabine and tenofovir if you are allergic to emtricitabine or tenofovir. Do not take if you also use other medicines that contain emtricitabine, tenofovir, lamivudine, or adefovir (such as Atripla, Combivir, Complera, Descovy, Dutrebis, Emtriva, Epivir, Epzicom, Genvoya, Hepsera, Odefsey, Stribild, Triumeq, Trizivir, or Viread).

If you take Truvada PrEP to reduce your risk of HIV infection: You must have a negative HIV test immediately before you start taking the medicine.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skipping doses may increase the risk of your virus becoming resistant to antiviral medicine. Try not to miss any doses.

Get your prescription refilled before you run out of medicine completely.

side effects

  • Get emergency medical help if you have signs of an allergic reaction
  • Mild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired.
  • Call your doctor at once if you have:
  • symptoms of new HIV infection--fever, night sweats, tiredness, muscle or joint pain, sore throat, vomiting, diarrhea, rash, swollen glands in your neck or groin;
  • sudden or unusual bone pain
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • liver problems--nausea, swelling around your midsection, upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).


Dosage Form: Film-coated tablets containing 200 mg emtricitabine and 300 mg tenofovir disoproxil fumarate (equivalent to 245 mg of tenofovir disoproxil).

The recommended dose of Truvada for adults 18 years or older is one tablet once a day. Patients with lowered creatinine clearance (30 to 49 ml/min) should receive one tablet every 48 hours. Truvada should not be prescribed for patients requiring dosage adjustment, such as those with reduced renal function (creatinine clearance less than 30 ml/min or requiring hemodialysis).