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What is solifenacin?

Solifenacin is a prescription drug. It comes only as an oral tablet.

Solifenacin oral tablet is available only as the brand-name drug VESIcare. It’s not available as a generic drug.

How it works

Solifenacin belongs to a class of drugs called urinary antagonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Normally, when your bladder fills with urine, it expands. Once it’s fully expanded, it sends a message to your brain telling it you’re ready to urinate. When you urinate, the muscles in your bladder contract, which starts a flow of urine.

Dosing Information

The recommended dose of VESIcare is 5 mg once daily. If the 5 mg dose is well tolerated, the dose may be increased to 10 mg once daily. VESIcare should be taken with water and swallowed whole. VESIcare can be administered with or without food.

How is this medicine (Solifenacin) best taken?

Use solifenacin as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Swallow whole with a drink of water.
  • To gain the most benefit, do not miss doses.
  • Keep taking solifenacin as you have been told by your doctor or other health care provider, even if you feel well.

Solifenacin Interactions

Tell your doctor about the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • amiodarone (Cordarone, Pacerone)
  • antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral)
  • carbamazepine (Tegretol)
  • cimetidine (Tagamet)
  • cisapride (Propulsid)

Solifenacin and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Solifenacin falls into category C. There are no well-controlled studies that have been done in pregnant women. Solifenacin should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.