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Sofosbuvir & Daclatasvir

Sofosbuvir & Daclatasvir

Sofosbuvir, Daclatasvir Combination Effective

Sofosbuvir and daclatasvir combination therapy (SOF/DCV) is safe and effective for real-world treatment of patients with liver cirrhosis associated with hepatitis C virus (HCV) genotype 4, according to a study published in Alimentary Pharmacology & Therapeutics.

The randomized, multicenter, open-label study took place in 2016 at 4 separate clinical settings in Egypt. A total of 551 patients with hepatitis C virus genotype 4 and related liver cirrhosis were included in the study; 119 (21.6%) had been previously treated and 432 (78.4%) were naive to treatment.

How to take Daklinza?

Daklinza must be given in combination with sofosbuvir and it should not be used alone.

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using this medicine.

Daklinza is usually taken with other antiviral medicines once per day for 12 weeks. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Miss a dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Use Daklinza regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Daklinza side effects

Get emergency medical help if you have signs of an allergic reaction to Daklinza: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or

new or worsening liver symptoms - loss of appetite, upper stomach pain; dark urine, clay-colored stools; jaundice (yellowing of the skin or eyes).