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Sodium Hyaluronate

Sodium Hyaluronate

What Is Sodium Hyaluronate?

Sodium hyaluronate is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.

Sodium hyaluronate is used to treat knee pain caused by osteoarthritis.

Sodium hyaluronate is usually given after other arthritis medications have been tried without successful treatment of symptoms.

Sodium hyaluronate may also be used for purposes not listed in this medication guide.

How is sodium hyaluronate given?

Sodium hyaluronate is injected directly into your knee joint. A healthcare provider will give you this injection.

Sodium hyaluronate is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.

To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.


This medication is used to protect skin ulcers, burns, or wounds from irritation so that the skin can heal properly. Hyaluronate is the same as a natural substance that is found in your body. It works by forming a protective layer over the affected area.

How to use Sodium Hyaluronate Cream

Use this product on the skin only. Wash your hands before and after each use. Before using, wash and disinfect the affected area as directed by your doctor. Gently apply a thin layer of the medication to the affected areas of the skin, usually 2 to 3 times daily or as directed by your doctor. Cover the affected area as directed.

Sodium Hyaluronate Interactions

For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.

Sodium hyaluronate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected
  • nausea, stomach pain
  • trouble walking
  • swelling in your hands or feet
  • back pain, joint pain, muscle pain