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What is Sitagliptin?

Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Sitagliptin is a diabetes drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

How to use Sitagliptin Tablet

Read the Medication Guide provided by your pharmacist before you start using sitagliptin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food, as directed by your doctor, usually once daily.

The dosage is based on your medical condition, kidney function, and response to treatment. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Carefully follow the medication treatment plan, meal plan, and exercise program your doctor has recommended.Check your blood sugar regularly as directed by your doctor. Keep track of the results, and share them with your doctor. Tell your doctor if your blood sugar measurements are too high or too low. Your dosage/treatment may need to be changed.

How it works

Sitagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Insulin is a chemical in your body that helps remove sugar from your blood and moves it to cells, where it can be used for energy. Hormones in your body called incretins regulate the production and release of insulin. Sitagliptin works by protecting incretin hormones so they aren’t broken down too quickly. This helps your body use insulin better and lowers your blood sugar.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Pancreatitis. Symptoms can include:
  • severe pain in your stomach that won’t go away, and that can be felt from your stomach through your back
  • vomiting
  • Low blood sugar.* Symptoms can include:
  • intense hunger
  • nervousness
  • shakiness
  • sweating, chills, and clamminess
  • dizziness
  • fast heart rate
  • lightheadedness
  • sleepiness
  • confusion
  • blurred vision
  • nightmares and crying out in your sleep

What are some things I need to know or do while I take Sitagliptin?

Tell all of your health care providers that you take sitagliptin. This includes your doctors, nurses, pharmacists, and dentists.Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.Check your blood sugar as you have been told by your doctor.Have blood work checked as you have been told by the doctor. Talk with the doctor.

Talk with your doctor before you drink alcohol.

Follow the diet and workout plan that your doctor told you about.

It may be harder to control your blood sugar during times of stress like when you have a fever, an infection, an injury, or surgery. A change in level of physical activity or exercise and a change in diet may also affect your blood sugar. Talk with your doctor.

A skin reaction called bullous pemphigoid has happened with drugs like this one. Sometimes, people have had to go to the hospital. Call your doctor right away if you have blisters or if your skin starts to break down.