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Sildenafil Review

Sildenafil Review

What is sildenafil?

Sildenafil is an oral medication called a phosphodiesterase-5 (PDE5) inhibitor approved for the treatment of pulmonary arterial hypertension (PAH) in World Health Organization (WHO) Group 1 patients. The goal of this therapy is to improve exercise ability and delay clinical worsening. Research studies showing the effectiveness of the medication included mostly patients with symptoms that were rated as WHO Functional Class II-III.Sildenafil is marketed as Revatio® for PAH and was approved by the United States Food and Drug Administration (FDA) in 2005. Sildenafil is also marketed as Viagra® which is FDA-approved for the treatment of erectile dysfunction but not for the treatment of PAH.

Side Effects

Major and Minor Sildenafil Side Effects

  • flushing
  • stuffy nose
  • headache
  • memory problems
  • upset stomach
  • back pain
  • low blood pressure
  • faint feeling
  • dizziness
  • shortness of breath

How long does Viagra take to work?

The effects of Viagra will vary from person to person. As a general rule, Viagra is thought to start working in most people from around 30 minutes after taking the drug. It is important to understand that taking Viagra tablets alone will not cause an erection. Viagra must be taken in combination with some form of sexual stimulation (visual, tactile or otherwise) in order for an erection to occur.

How long does Viagra last?

The length of time Viagra lasts for will also vary from person to person, but it has been known to work for up to 5 hours at a time, when used alongside sexual stimulation. Most men will find, however, that the effects of the pill will start to wear off 2-3 hours after first taking it. There are certain factors that will contribute to how long Viagra will last for in your individual situation, and you should always discuss your full medical history and details of any medicines you are currently taking before starting a course of treatment with Viagra.

Dosage

For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, Viagra may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day. Ask your health care provider any questions you may have about how to use Viagra.

Storage

Store Viagra at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Viagra out of the reach of children and away from pets.

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