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Sildenafil Contraindications

Contraindications of Sildenafil

Sildenafil citrate is a drug used for the treatment of male impotence. The drug is popularly known as Viagra or blue pill and it is the most popular medicine in the world since last 2 decades. This medicine has saved thousands of relationships and millions of men from embarrassment of erectile dysfunction.

However, from a past few years individuals have started abusing this drug. There are many myths related to the drug and these myths have promoted the over use and abuse of the medicine. As a result, patients are getting more side-effects than the optimum results. The side-effects in turn affect the performance of the male individual in the bedroom.

SIDE EFFECTS

The following are discussed in more detail in other sections of the labeling:

  • Cardiovascular
  • Prolonged Erection and Priapism
  • Effects on the Eye
  • Hearing Loss
  • Hypotension when Co-administered with Alpha-blockers or Anti-hypertensives
  • Adverse Reactions with the Concomitant Use of Ritonavir
  • Combination with other PDE5 Inhibitors or Other Erectile Dysfunction Therapies
  • Effects on Bleeding
  • Counseling Patients About Sexually Transmitted Diseases

Effects on Bleeding

There have been postmarketing reports of bleeding events in patients who have taken sildenafil contraindications. A causal relationship between sildenafil contraindications and these events has not been established. In humans, sildenafil contraindicationshas no effect on bleeding time when taken alone or with aspirin. However, in vitro studies with human platelets indicate that sildenafil potentiates the antiaggregatory effect of sodium nitroprusside (a nitric oxide donor). In addition, the combination of heparin and sildenafil contraindications had an additive effect on bleeding time in the anesthetized rabbit, but this interaction has not been studied in humans.

The safety of sildenafil contraindicationsis unknown in patients with bleeding disorders and patients with active peptic ulceration.

DOSAGE

For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, Viagra may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.

STORAGE

Store Viagra at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Viagra out of the reach of children and away from pets.

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