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Sildenafil 100 Mg Duracion

Sildenafil 100 Mg Duracion

Nowadays sildenafil citrate is the most commonly used medication to treat erectile dysfunction. Such popularity of this sexual enhancer can be explained mostly by its high efficacy, as well as its non-invasive oral form. Another key advantage is that Viagra not only improves the ability to maintain an erection, but also increases the quality of sexual intercourse, extends the duration of sexual intercourse and intensifies orgasm.

How does Viagra work?

Sildenafil is a selective inhibitor of cyclic guanosine monophosphate specific phosphodiesterase type 5 (PDE-5) in the penis where PDE-5 is responsible for the decomposition of cyclic guanosine monophosphate (cGMP). The inhibition of this enzyme leads to the accumulation of cGMP, smooth muscle relaxation and increased blood flow in the penis. This process helps to achieve a strong erection in the case of sexual stimulation.

In other words, Viagra is very effective for the relaxation of blood vessels and smooth muscles, as well as the stimulation of the senile circulation better in the pelvic organs that is so important to get enough erection for sexual activity. 
On average, erectile dysfunction is improved within 14-20 minutes after ingestion of the drug. How long is Viagra? It is worth mentioning that during the activity of Viagra also reduces the period necessary to recover the organism between sexual activities.

Viagra effect duration

Without a doubt, the duration of the effect of Viagra is what interests all patients so much. It should be noted that this period of the therapeutic effect is quite individual and depends on many factors, for example the nutritional habits of the patient, special characteristics of the digestive system and the body's reactions in sildenafil and other additional components.
In general, the duration of its effect makes between 4 and 6 hours according to the official data of the manufacturer. However, some patients have reported improvement of erectile function up to 12 hours after the administration of a pill.

During the use of the remedies for potency it is very important to follow the appropriate dose. Take the dose of Viagra prescribed by your health care provider, do not take this medication without the specialist's directions. It is also necessary to remember that the intake of a higher dose does not prolong the duration of the effect, but vice versa can cause the manifestation of serious side effects. Also, remember that the frequency of manifestation of general side effects such as headache, digestive problems, palpitation, nosebleed and others, is associated with overdose of the preparation. It is not allowed to take more than one dose during the 24 hours, even if the patient has not had any therapeutic effect after the first intake of the drug. The manifestation of side effects is also possible even in such type of overdose, so avoid the administration of the second dose over a single day. To adjust the appropriate dose, consult your doctor.

When does Viagra effect last more than 6 hours?

Some factors can affect the average duration of any medication. Among other things, the effect of Viagra can be affected by the following factors:

  1. Advanced age. In patients older than 65 years, sildenafil is eliminated from the body more slowly because of some metabolic disorders. Therefore, Viagra often works more slowly in patients of legal age than in younger patients. In this context, doctors more frequently prescribe the lower doses of sildenafil for patients who are already 65 years of age or older.
  2. Use after eating. In such a case the enhancing effect arrives more slowly than within an hour. In this context, please remember that high-fat food can completely block the effect of Viagra.
  3. Consumption of alcohol. The consumption of alcoholic beverages worsens the functioning of the liver which prevents the rapid elimination of sildenafil from the body. However, the use of the remedy for potency can be ineffective because in the drunken state sexual function is also diminished, which can not yet be improved by the intake of such a strong drug. In addition, serious side effects may arise from the liver, just as the heart receives the double blow.
  4. High doses of sexual enhancers. The general rule is that higher doses of medications provide the most lasting effect. It turns out that a dose of 100 mg of sildenafil lasts a little longer than 25 mg of sildenafil. However, this can be explained by a simple fact that lower doses provide a milder effect that is not as noticeable to patients. Anyway, always take the dose prescribed by the doctor.
  5. Renal failure Remember that sildenafil decomposes more slowly in patients with kidney failure. In this case, the doctor must correctly adjust the dose according to the patient's conditions.
  6. Interactions with other products. Some preparations and medications should not be administered with Viagra, for example antibiotics such as rifampicin. Such a combination can be very dangerous for life. For this reason, consult your doctor about the permitted drug interactions.

As a general rule, sildenafil is eliminated from the body for 4 hours. That means that the normal effect lasts between 4 and 6 hours.

Efficacy of Viagra compared to other PDE-5 inhibitors

There are several active substances that can be used successfully for the treatment of erectile dysfunction. Among these active ingredients the best known are tadalafil, vardenafil, avanafil and udenafil. All these principles belong to the group of phosphodiesterase type 5 inhibitors (PDE-5).
The main difference between these preparations is that some can be absorbed more quickly and therefore works almost immediately, others are absorbed more slowly and therefore provide a more lasting effect. For example, Levitra (vardenafil) and Zydena (udenafil) are faster than Viagra with the duration of effect of 6 hours, while Cialis (tadalafil) has the significantly longer lasting potentiating effect - up to 36 hours. 
Avanafil (active substance of Spedra) also relieves the symptoms of erectile dysfunction for 6 hours which is equivalent to the effect of Viagra. The choice of PDE-5 inhibitor should be made by the doctor who evaluates all patient conditions and prescribes the correct dose.