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Sildenafil & Duloxetine

Sildenafil & Duloxetine

What is Viagra With Duloxetine?

The combination of Viagra and duloxetine is a powerful medicine to address the issue of male impotency. It is prescribed to treat erectile dysfunction and premature ejaculation. It is sometimes prescribed for pulmonary arterial hypertension.

Class and Mechanism of Action

Viagra contains Sildenafil as an active ingredient. It is a phosphodiesterase type 5 inhibitor. Its PDE5 inhibiting action releases more of cGMP in the Corpus Cavernosum of a penis. An increased level of cGMP relaxes the smooth muscles and improves blood flow. Duloxetine is a serotonin-norepinephrine reuptake inhibitor. It inhibits serotonin reuptake, thereby increasing its amount exponentially in the blood. It’s action at the postsynaptic cleft increases thereby preventing premature ejaculation.

Warnings and Precautions

Inform your doctor about other disease conditions you are suffering from and the medications taking. Do not take it with medicines containing nitrates. Do not consume alcohol. Seek immediate medical help if your erection lasts for more than 4 hours.

Possible Side Effects

  • Flushing
  • Headache
  • Dyspepsia
  • Nasal discharge and stuffiness
  • Vision disturbances (blurred vision, photophobia, blue-tinted vision)

Adverse Effects

As many other powerful tools, Malegra may induce some unwanted effects. While taking this preparation there may happen the following adverse effects asthenia, abdominal pain, back pain, infection, vasodilation, diarrhea, nausea, joint and muscle pain, dizziness, nasal congestion, respiratory dysfunctions, blurred vision, conjunctivitis, urinary tract infections, hypotension, palpitation, vomiting, too long erection, eye pains, redness of the eyes and some allergic reactions.

Malegra – a Dependable Viagra’s Generic

Nowadays, modern medicine and science have provided us with billions of different preparations aimed to combat this or that ailment. There exists a great variety of means that are targeted to overcome problems with erectile dysfunctions as well. Everybody knows famous Viagra, which was the first of this series, and which is still most popular and reliable. Within time, there have appeared lots of its generics. Generic is a preparation identical to the original, but costs less. Sometimes these generics may be even better than the original. One of such is Malegra, Viagra’s generic.

malegra tablets

Its major constituent is also Sildenafil citrate and it works the same way. It enhances blood inflow to the pelvic organs and in such way guarantees firm and dependable erection. But you should remember that erection can be gained only when there is natural arousal. It will not come after simple using tablets.

Malegra has passed many clinical trials and is considered to be quite dependable and efficacious preparation that helps to regain normal erection for men.


Commonly these unwished events happen rarely and are not serious. In most occasions, they take place when examinees overdose themselves with tablets or rapidly change the dosage. At any rate, you ought to consult a specialist first and only afterwards change your dosage, if you feel that it is not effectual enough, or if it is harmful for you and causes adverse effects. Any time you experience adverse effects of enormous severity immediately turn for help to professionals.