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Side Effects Raltegravir

Side Effects Raltegravir

What Is Raltegravir?

Raltegravir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Raltegravir is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Raltegravir is not a cure for HIV or AIDS.

Raltegravir may also be used for purposes not listed in this medication guide.

Raltegravir may cause a severe skin reaction that can be fatal. Stop taking this medicine and get emergency medical help if you have skin redness or a rash that spreads and causes blistering and peeling.


Raltegravir is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Raltegravir is known as an integrase inhibitor. It blocks the virus from growing and infecting more cells.

Side Effect

Common side effects of Isentress include:

  • nausea
  • vomiting
  • diarrhea
  • stomach pain
  • headache
  • tired feeling
  • dizziness
  • sleep problems (insomnia)
  • changes in the shape or location of body fat

How should I take raltegravir?

Raltegravir comes in the following forms and strengths:

  • 400-mg film-coated tablets (brand name: Isentress).
  • 600-mg film-coated tablets (brand name: Isentress HD).
  • 25-mg and 100-mg chewable tablets (brand name: Isentress).
  • 100-mg single-use packets for oral suspension (brand name: Isentress).

Take raltegravir according to your health care provider’s instructions.

Take raltegravir by mouth, with or without food. Always swallow the film-coated tablets whole. The chewable tablets may be chewed or swallowed whole.

What should I do if I forget a dose?

If you miss a dose of raltegravir, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

How should raltegravir be stored?

Store raltegravir at room temperature, 68°F to 77°F (20°C to 25°C).

Do not use raltegravir if the original seal over the container opening is broken or missing.

Keep raltegravir film-coated and chewable tablets in the container that they came in and keep the container tightly closed. If the container has a small packet of drying agent (called a desiccant), do not remove it. The desiccant protects the medicine from moisture.

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