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Side Effects Of Glimepiride

Side Effects Of Glimepiride

What is glimepiride?

Glimepiride is a prescription drug. It comes as an oral tablet.

Glimepiride is available as the brand-name drug Amaryl and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

This drug may be used as part of a combination therapy. That means you need to take it with other drugs.

Glimepiride side effects

Glimepiride oral tablet doesn’t cause drowsiness, but it can cause other side effects.

More common side effects

The more common side effects that can occur with glimepiride include:

low blood sugar (hypoglycemia). Symptoms may include:

  • trembling or shaking
  • nervousness or anxiety
  • irritability
  • sweating
  • lightheadedness or dizziness
  • headache
  • fast heart rate or palpitations
  • intense hunger
  • fatigue or tiredness
  • headache
  • nausea
  • dizziness
  • weakness

unexplained weight gain

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

severe low blood sugar (less than 35 to 40 mg/dL). Symptoms may include:

  • mood changes, such as irritability, impatience, anger, stubbornness, or sadness
  • confusion, including delirium
  • lightheadedness or dizziness
  • sleepiness
  • blurred or impaired vision
  • tingling or numbness in your lips or tongue
  • headaches
  • weakness or fatigue
  • lack of coordination
  • nightmares or crying out in your sleep
  • seizures
  • unconsciousness

hypersensitivity (allergic) reactions. This drug can cause several types of allergic reactions, including:

  • anaphylaxis. This is a severe and possibly a life-threatening allergic reaction. Symptoms may include trouble breathing, swelling of your throat or tongue, hives, or difficulty swallowing.
  • angioedema. This involves swelling of your skin, the layers under your skin, and your mucous membranes (inside your mouth).
  • Stevens-Johnsons syndrome. This is a rare and serious disorder of your skin and mucous membranes (mouth and nose). It starts with flu-like symptoms and is followed by a painful red rash and blisters.

liver damage. Symptoms may include:

  • yellowing of your skin and the whites of your eyes (jaundice)
  • stomach pain and swelling
  • swelling in your legs and ankles (edema)
  • itchy skin
  • dark-colored urine
  • pale stool or tar-colored stool
  • constant sleepiness
  • nausea
  • vomiting
  • bruising easily

low blood cell or platelet counts. Symptoms may include infections and bruising or bleeding that doesn’t stop as quickly as normal.

low sodium levels (hyponatremia) and syndrome of inappropriate antidiuretic hormone secretion (SIADH). In SIADH, your body is unable to get rid of excess water by urinating. This leads to lower sodium levels in your blood (hyponatremia), which is dangerous. Symptoms may include:

  • nausea and vomiting
  • headache
  • confusion
  • loss of energy and fatigue
  • restlessness and irritability
  • muscle weakness, spasms, or cramps
  • seizures
  • coma

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