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Side Effects Of Cisplatin

Side Effects Of Cisplatin

Description

Nausea, vomiting, loss of appetite, diarrhea, and loss of taste may occur. Nausea and vomiting can be quite severe and persistent. Drug therapy is used to prevent or relieve nausea and vomiting. Not eating before your treatment may help relieve vomiting. Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Temporary hair loss may occur. Normal hair growth should return after treatment has ended.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: pain/burning/redness at the injection site, numbness/tingling/coldness/blue discoloration of the hands or feet, pain/redness/swelling of arms or legs, loss of reflexes, loss of balance, trouble walking, muscle cramps/spasms/weakness, neck or back pain, mouth or tongue sores, joint pain, swollen legs or feet, mental/mood changes, headache, fast/irregular heartbeat, blood in urine, vomit that looks like coffee grounds, black or bloody stools, painful or difficult urination, lower back or side pain, vision changes (e.g., blurred vision, seeing colors differently).Rarely, temporary vision loss may occur with cisplatin use. Normal vision usually returns after the end of treatment. Consult your doctor or pharmacist for more details and report this side effect immediately if it occurs.

Uses

Cisplatin is used to treat various types of cancer. It is a chemotherapy drug that contains platinum. It is used alone or in combination with other medications to slow or stop cancer cell growth

How it works

This chemotherapy drug destroys quickly dividing cells, such as cancer cells.

When you have cisplatin

You usually have cisplatin every 3 or 4 weeks as a course of several cycles of treatment. Or you might have it each week.

Tests during treatment

You have blood tests before starting treatment and during your treatment. They check your levels of blood cells and other substances in the blood. They also check how well your liver and kidneys are working.

Side Effect

The following side effects are common (occurring in greater than 30%) for patients taking Cisplatin:

  • Nausea and vomiting. Nausea may last up to 1 week after therapy. Anti-nausea medication is given before the infusion, and a prescription is also given for use after.Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia, and/or bleeding. Nadir: Meaning low point, is the point in time between chemotherapy cycles in which you experience low blood counts.Nadir: 18-23 days. Recovery: 39 daysKidney toxicity. Effects on kidney function are dose related, observed 10-20 days after therapy, and are generally reversible.Ototoxicity hearing loss, ringing in the ears.Blood test abnormalities (low magnesium, low calcium, low potassium)These are less
  • common side effects (occurring in 10-29%) for patients receiving Cisplatin Peripheral neuropathy: Although less common, a serious side effect of decreased sensation and paresthesia (numbness and tingling of the extremities) may be noted. Sensory loss, numbness and tingling, and difficulty in walking may last for at least as long as therapy is continued. These side effects may become progressively more severe with continued treatment, and your doctor may decide to decrease your dose. Neurologic effects may be irreversible.

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