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Rifampicin is an antitubercular medicine which helps to treat tuberculosis and meningococcal meningitis. It should be taken with other medicines to prevent the spread of infection. This medicine may cause reddish colouration of the urine, sweat, sputum and tears.

Side Effects

This drug may cause upset stomach, heartburn, nausea, menstrual changes, headache, drowsiness, or dizziness. If any of these effects persist or worsen, inform your doctor promptly.

This medication may cause urine, sweat, saliva, or tears to change color (yellow, orange, red, or brown). This effect is harmless and will go away when the medication is stopped. However, teeth and contact lens staining may be permanent.


Before taking rifampin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, liver problems (e.g., hepatitis), HIV infection, history of alcohol use/abuse.

This drug may make you dizzy or drowsy.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.


Missed Dose

If you miss a dose of Rifampicin , take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.


Seek emergency medical treatment or contact the doctor in case of an overdose.

Warnings for special population

Pregnancy - This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding - This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

General warnings

Liver injury - This medicine may cause liver injury, therefore should be used with caution. The liver function tests should be performed before starting the treatment. The dose should be adjusted based on the severity of liver disease.

Diabetes - This medicine may alter the blood glucose levels. Inform the doctor about your medical condition before starting the treatment. Monitoring of blood glucose levels is necessary.

Drug-resistance - Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.