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Ramipril

Ramipril

About ramipril

Ramipril is a medicine widely used to treat high blood pressure and heart failure. It's also prescribed after a heart attack.

Ramipril helps to prevent future strokes, heart attacks and kidney problems. It also improves your survival if you're taking it for heart failure or after a heart attack.

This medicine is available on prescription. It comes as tablets, capsules and as a liquid that you swallow.

How and when to take it

It's usual to take ramipril once or twice a day.

You may be advised to take your first dose before bedtime, because it can make you dizzy. After the very first dose, you can take ramipril at any time every day. Try to take it at the same time every day.

How much will I take?

The dose of ramipril you take depends on why you need the medicine. Take it as instructed by your doctor.

To decide the correct dose for you, your doctor will check your blood pressure and ask you if you are getting any side effects. You may also have blood tests to check how well your kidneys are working and the amount of potassium in your blood.

Depending on why you're taking ramipril, the usual starting dose is between 1.25mg once a day and 2.5mg twice a day. This will be increased gradually over a few weeks to a usual dose of:

2.5mg to 5mg once a day for high blood pressure

5mg twice a day or 10mg once a day for heart failure or after a heart attack

If you're bothered by side effects with ramipril you may stay on a lower dose.

The maximum dose is 5mg twice a day or 10mg once a day.        

Dosage

Missed Dose

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of overdose.

Before taking this medicine

You should not use ramipril if you are allergic to it, or if:

you have a history of angioedema;

you recently took a heart medicine called sacubatril; or

if you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, or trandolapril.

Do not take ramipril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto).

If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

You may also need to avoid taking ramipril with aliskiren if you have kidney disease.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

kidney disease (or if you are on dialysis);

liver disease;

a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis; or

if you are also taking telmisartan (Micardis).

How should I take ramipril?

Take ramipril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Ramipril can be taken with or without food.

Swallow the tablet whole.

You may open the capsule and sprinkle the medicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing easier. Swallow without chewing. You may store the mixture for up to 24 hours at room temperature, or up to 48 hours in a refrigerator.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking ramipril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.

Your blood pressure will need to be checked often, and you may need frequent blood tests to check your potassium levels.

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