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What Is Prochlorperazine?

Prochlorperazine is a prescription drug classified as an anti-nausea and anti-vomiting medicationIt's also marketed under the brand names Compro and Procomp, and is used for controlling severe nausea and vomiting.

It's not a cure for the condition, but may help manage the symptoms. It works by controlling abnormal excitement in the brain.

Prochlorperazine is also used to treat generalized that is non-psychotic, but experts say that for most patients it should not be the first treatment due to the risks associated with its use.

The Food and Drug Administration (FDA) approved prochlorperazine as Compazine in 1999. GlaxoSmithKline made Compazine, but it is no longer on the market.

Now, the medicine is made in generic form by several companies as both an oral tablet and a suppository.

Prochlorperazine Dosage

Prochlorperazine in suppository form comes in 25 milligram (mg) doses that can be taken twice a day. Tablets come in 5 and 10 mg formulas with a recommended dose of 10 to 40 mg a day.

While adults can take tablets three or four times a day, children's doses are usually given one to three times a day.

Prochlorperazine should not be given to children younger than two years or weighing less than 20 pounds.

Prochlorperazine Overdose

If you notice jitteriness, drooling, a shuffling walk, or experience seizures or an irregular heartbeat, these may all be symptoms of overdose. Call your doctor or go to the nearest emergency room immediately.