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What Is Procainamide?

The drug was once sold under the brand names Procan and Pronestyl. But these brands, along with oral forms of the medicine, are no longer available in the United States.

Procainamide belongs to a class of drugs called anti-arrhythmics. It works by blocking certain electrical signals in the heart.

The U.S. Food and Drug Administration (FDA) approved procainamide in 1950. It's manufactured by Hospira, Inc.

Procainamide Warnings

Procainamide contains a black box warning because long-term use of the medicine can lower the number of cells in your bone marrow, and can also cause an autoimmune disease characterized by inflammation and a variety of other symptoms.Anti-arrhythmic drugs, including procainamide, may increase your risk of death. The drug also contains a black box warning because of this risk.

Procainamide should only be used to treat life-threatening conditions.Tell your doctor if you've had in the past two years before taking this medicine.Procainamide contains another black box warning because it can cause potentially fatal changes in your blood cell counts.

Procainamide Dosage

Procainamide is injected into a muscle, or infused into a vein through an IV.

Typically, a nurse or other healthcare provider will administer procainamide in a hospital setting.Your dosage will be based on your general health, medical condition, age, and weight.

Procainamide Overdose

Symptoms of a procainamide overdose may include:

  • Dizziness
  • Difficulty breathing
  • Severe drowsiness
  • Tremors
  • Fast or irregular heartbeat

If you suspect an overdose, contact a poison control center or emergency room immediately.