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What Is Piroxicam (Feldene)?

Piroxicam is the generic form of the brand-name drug Feldene, an anti-inflammatory drug used to relieve pain, swelling, stiffness, and tenderness caused by arthritis.

The medicine is in a class of drugs known as non-steroidal anti-inflammatory drugs .It works by stopping certain substances in the body that may cause inflammation.

The Food and Drug Administration (FDA) approved piroxicam in 1982. It’s manufactured as Feldene by Pfizer, Inc.

Piroxicam Warnings

Piroxicam carries a black-box warning because it may increase the risk in certain people. This risk may be greater if you already have heart problems or if you take piroxicam for a long time.

 Tell your doctor if you or anyone in your family has or has ever had:

  • Heart disease
  • A heart attack
  • Diabetes

 Don’t take piroxicam right before or right after bypass heart surgery.

Get emergency medical help right away if you experience any of the following symptoms while taking piroxicam:

  • Shortness of breath
  • Chest pain
  • Weakness on one side of your body
  • Slurred speech

 This medicine also carries a black-box warning because it may increase your risk of developing stomach ulcers and bleeding. These problems can be serious and sometimes fatal.

Elderly people and those who take NSAIDs such as piroxicam for a long time have a greater risk of developing intestinal problems. Consuming alcohol may also increase your risk of stomach bleeding or ulcers.

Piroxicam Interactions

Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially those listed in the Piroxicam Warnings section above, or any of the following

  • Angiotensin-converting enzyme (ACE) inhibitors such as (Lotensin),(Capoten),  (Vasotec), (Monopril), lisinopril (Prinivil, Zestril),(Univasc), Aceon),(Accupril), (Altace), and(Mavik)
  • (water pills)
  • (Eskalith, Lithobid)
  • Medications for diabetes
  • Methotrexate (Rheumatrex)
  • Phenytoin

Piroxicam Dosage

Piroxicam comes as a tablet to take by mouth. It’s typically taken once or twice daily.Take this medicine around the same time each day with a full glass of water.You can take piroxicam with food if it upsets your stomach.Follow the instructions on your prescription label carefully. Don’t take more or less piroxicam than your doctor recommends.