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Pirfenidone

Pirfenidone

What Is Pirfenidone?

Pirfenidone is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your lungs. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work.

Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen.

The cause of IPF is often unknown, but this condition is a progressive disease that can be fatal. Pirfenidone is not a cure for IPF, but this medicine may slow the progress of this disease.Pirfenidone may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.You should not use pirfenidone if you are allergic to it.

To make sure pirfenidone is safe for you, tell your doctor if you have:

  • liver disease;
  • kidney disease; or
  • if you smoke.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether pirfenidone passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Pirfenidone Interactions

Avoid exposure to sunlight or tanning beds. Pirfenidone can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Tell your doctor if you are also using antibiotic medicine, which can also make you more sensitive to sunlight.Avoid smoking while taking this medicine. Smoking could make pirfenidone less effective.

Other drugs may interact with pirfenidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Pirfenidone Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe ongoing stomach pain, vomiting, diarrhea;
  • burning or pain in your esophagus or throat; or
  • liver problems--stomach pain (upper right side), easy bruising or bleeding, feeling tired, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
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