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Pazopanib Tablets

pazopanib tablets

Pazopanib (Votrient)

Read about pazopanib, how you have it and other important information about taking this cancer drug. Pazopanib is pronounced pas-op-ann-ib. It is also called Votrient. It is a treatment for:  advanced kidney cancer (renal cancer some types of soft tissue sarcoma Researchers are looking at pazopanib as a treatment for a number of other types of cancer.

Drug Description

votrient (pazopanib) is a tyrosine kinase inhibitor (tki). pazopanib is presented as the hydrochloride salt, with the chemical name 5-[[4-[(2,3-dimethyl-2h-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide. pazopanib hydrochloride is a white to slightly yellow solid. it is very slightly soluble at ph 1 and practically insoluble above ph 4 in aqueous media. tablets of votrient are for oral administration. each 200-mg tablet of votrient contains 216.7 mg of pazopanib hydrochloride, equivalent to 200 mg of pazopanib free base.

Important information

Other medicines, foods and drink

Cancer drugs can interact with some other medicines and herbal products. Tell your doctor or pharmacist about any medicines you are taking. This includes vitamins, herbal supplements and over the counter remedies.

Treatment for other conditions

Always tell other doctors, nurses, pharmacists or dentists that you’re having this treatment if you need treatment for anything else, including teeth problems.

Slow wound healing

This drug can slow wound healing. If you need to have an operation you may need to stop taking it for a while beforehand. Your doctor will let you know when you can start taking it again.

Pregnancy and contraception

This treatment might harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for a few months afterwards. Talk to your doctor or nurse about effective contraception before starting treatment.

Dosage

the recommended starting dose of votrient is 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal) [see clinical pharmacology]. the dose of votrient should not exceed 800 mg. do not crush tablets due to the potential for increased rate of absorption which may affect systemic exposure [see clinical pharmacology]. if a dose is missed, it should not be taken if it is less than 12 hours until the next dose.

How it works

Pazopanib is a type of targeted cancer drug called a tyrosine kinase inhibitor (TKI). Tyrosine kinases are proteins which act as chemical messengers (enzymes) in cells. There are a number of different tyrosine kinases and they stimulate cancer cells to grow. Pazopanib blocks a number of these proteins and is called a multi tyrosine kinase inhibitor (multi TKI). It stops cancer cells forming blood vessels that they need in order to grow. This is called anti angiogenesis treatment.

Taking your tablets or capsules

Whether you have a full or empty stomach can affect how much of a drug gets into your bloodstream. You should take the right dose, not more or less. Never stop taking a cancer drug without talking to your specialist first. Don't take extra tablets if you forget to take a dose. Just take your next dose at the usual time.

Know More About This Medicine and Buy Now : MedyPharma.com

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