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Norfloxacin Dosage

norfloxacin dosage

What Is Norfloxacin?

Norfloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Norfloxacin fights bacteria in the body.

Norfloxacin is used to treat different bacterial infections of the prostate or urinary tract (bladder and kidneys). Norfloxacin is also used to treat gonorrhea.

Norfloxacin may also be used for purposes not listed in this medication guide.

You should not use this medication if you have ever had swelling or tearing of a tendon caused by taking norfloxacin or similar antibiotics.

You may not be able to use norfloxacin if you have a muscle disorder. Tell your doctor if you have a history of myasthenia gravis.

Norfloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This effect may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant.

Stop taking norfloxacin and call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

You should not use this medication if you are allergic to norfloxacin, or if:

  • you have ever had swelling or tearing of a tendon caused by taking norfloxacin or similar antibiotics; or
  • you are allergic to other fluoroquinolones (ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, ofloxacin, and others).

You may not be able to use norfloxacin if you have a muscle disorder. Tell your doctor if you have a history of myasthenia gravis.

Side Effects of Norfloxacin

Norfloxacin can cause side effects that may be serious. See "Drug Precautions".

The most common side effects of norfloxacin include:

  • dizziness
  • nausea
  • diarrhea
  • heartburn
  • headache
  • stomach (abdominal) cramping
  • weakness
  • changes in certain liver function tests

These are not all the possible side effects of norfloxacin. Tell your healthcare provider about any side effect that bothers you or that does not go away.

General Instructions

Take Norfloxacin 400 MG Tablet one hour before or two hours after the food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking Norfloxacin 400 MG Tablet before completion of course.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Warnings for special population

Pregnancy - This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding - Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

Tendinitis and tendon rupture - Use of Norfloxacin 400 MG Tablet will increase the risk to develop tendinitis or tendon rupture during the treatment or several months after treatment. It will affect the shoulder, hand, back of the ankle, or other parts of the body. The risk is more if you are above 60 years of age and have a history of kidney, heart, or lung transplant or any joint disease. You are also at high risk if you are on corticosteroids like dexamethasone, methylprednisolone or prednisone.

Drug-resistance - Usage of Norfloxacin 400 MG Tablet without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Pediatric use - The safety and effectiveness of Norfloxacin 400 MG Tablet have not been established in children and adolescents less than 18 years of age.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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