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Nitazoxanide

Nitazoxanide

Introduction

Nitazoxanide is an antimicrobial with activity against several parasitic worms and protozoa that is used predominantly in the United States in treatment of giardiasis and cryptosporidiosis.  Nitazoxanide therapy has not been reported to cause serum aminotransferase elevations during therapy or clinically apparent liver injury.

Uses

This medication is used to treat diarrhea caused by certain parasite infections of the intestines (Cryptosporidium parvum and Giardia lamblia).

How to use Nitazoxanide Suspension For Reconstitution

Take this medication by mouth with food as directed by your doctor, usually every 12 hours for 3 days.

If you are taking the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Children 11 years old or younger should take the liquid form of nitazoxanide, but not the tablets. For children, the dosage is based on age.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Take this drug at evenly spaced intervals.

Why is this medication prescribed?

Nitazoxanide is used to treat diarrhea in children and adults caused by the protozoa Cryptosporidium or Giardia. Protozoa are suspected as the cause when diarrhea lasts more than 7 days. Nitazoxanide is in a class of medications called antiprotozoal agents. It works by stopping the growth of certain protozoa that cause diarrhea.

How should this medicine be used?

Nitazoxanide comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken with food every 12 hours for 3 days. Take nitazoxanide at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nitazoxanide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

Nitazoxanide Interactions

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Other drugs may interact with nitazoxanide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Precautions

Before taking nitazoxanide, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, a weakened immune system (such as HIV infection).

The liquid form of this medication contains sugar. Caution is advised if you have diabetes. Ask your doctor or pharmacist about using this product safely.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

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