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Naproxen Maximum Dosage

Naproxen Maximum Dosage

Usual Adult Dose for Ankylosing Spondylitis

May increase to 1500 mg orally once a day for a limited time up to 6 months in patients requiring higher levels of anti-inflammatory/analgesic activity.

When treating patients, especially at higher doses, sufficient increased clinical benefit should be observed to offset the potential for increased risk of adverse events.

Symptomatic improvement of arthritis is usually observed within 1 week; however, treatment for 2 weeks may be required to achieve therapeutic benefit.


For the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis

What is the maximum daily dosage for Aleve (naproxen)?

You should take one tablet every 8 to 10 hours until symptoms abate, although for the first dose you may take two tablets. The maximum adult dose is two tablets within an 8 to 10 hour period and three tablets within a 24-hour period. Aleve should not be taken for longer than 10 days unless recommended by your doctor. You should only give Aleve to a child under 12 years old if recommended by a doctor. Do not take more than the recommended dose of Aleve or overdose may occur.

How do I take naproxen and what is the dose?

Naproxen tablets should be taken with or after food. This helps avoid irritating the stomach and causing indigestion or abdominal pain.

Some types of naproxen tablet are 'gastro-resistant', meaning they have a special coating designed to help protect the stomach. This type of naproxen tablet can be taken either with or without food, but they must be swallowed whole with a drink - don't break, crush or chew these tablets, because this will damage the special coat. Also don't take indigestion remedies (antacids) in the two hours before or after taking these tablets, as they will stop the protective coat from working.

Naproxen side effects

The most common side effects from naproxen are:

  • rash,
  • ringing in the ears,
  • headaches,
  • dizziness,
  • drowsiness, abdominal pain, nausea,
  • diarrhea,
  • constipation,
  • heartburn,
  • fluid retention, and
  • shortness of breath.

How long can I take naproxen for?

If you have bought naproxen without a prescription for period pain, you shouldn't use it for more than three days at a time in each month.

If you have more long-term or ongoing pain, for example because you are recovering from an injury or you have arthritis, your doctor may ask you to take naproxen every day on a regular basis. This gives a better anti-inflammatory effect and avoids the painkilling effect wearing off, which will provide better pain relief.

If you need to take naproxen for long periods of time your doctor may also prescribe you a medicine to help protect your stomach.

Can I drink alcohol with naproxen?

Yes, it's usually fine to drink alcohol in moderation if you're taking naproxen. Just be aware that high doses or long-term use of naproxen carry a risk of irritating the stomach lining, and drinking alcohol above the daily recommended limit can increase this risk.

Are ibuprofen and naproxen safe to take if I am pregnant or breastfeeding?

There are no adequate studies of ibuprofen in pregnant women. Therefore, ibuprofen is not recommended during pregnancy. Ibuprofen should be avoided in late pregnancy due to the risk of premature closure of the ductus arteriosus in the fetal heart.

Ibuprofen is excreted in breast milk but the American Academy of Pediatrics states that ibuprofen is compatible with breastfeeding.

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