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Nabumetone Overview

Nabumetone is a prescription medication used to relieve the pain and swelling of osteoarthritis and rheumatoid arthritis. Nabumetone belongs to a group of medications called non-steroidal anti-inflammatory drugs (NSAIDs), which work by stopping substances in your body that cause inflammation and pain.

This medication comes in tablet form and is taken once or twice daily, with or without food.


Nabumetone is used to reduce pain, swelling, and joint stiffness from arthritis. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.

Side effects of nabumetone

Most patients, benefit from nabumetone and other NSAIDs with few side effects. However, serious side effects can occur, and generally tend to be dose-related. Therefore, it is advisable to use the lowest effective dose to minimize side effects. The most common side effects of nabumetone involve the gastrointestinal system, and these include:

  • abdominal pain
  • cramping
  • nausea
  • gastritis

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Nabumetone and Alcohol

Consuming alcohol while taking this medicine can increase your risk of stomach bleeding. You should not drink alcohol while taking nabumetone.

Nabumetone Dosage

The recommended starting dose for people with osteoarthritis or rheumatoid arthritis is 1,000 milligrams (mg) daily of nabumetone as a single dose. Some patients may take up to 2,000 mg daily. Doses can be divided and given twice a day.

You can take nabumetone with or without food. You should not lie down for at least 10 minutes after taking this drug.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.