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Methimazole is used to treat overactive thyroid (hyperthyroidism). It works by stopping the thyroid gland from making too much thyroid hormone.

How to use Methimazole

Take this medication by mouth with or without food as directed by your doctor, usually 3 times a day (every 8 hours).

Dosage is based on your medical condition and response to treatment. For children, the dosage is also based on their weight.

Take this medication exactly as directed. Do not increase your dose or take it more often than prescribed. Your condition will not improve faster, and your risk of side effects will increase.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor.

Tell your doctor if your condition does not improve or if it worsens.

What are the side effects of methimazole?

Methimazole is generally well-tolerated with side effects occurring in 3 out of every 100 patients. The most common side effects are related to the skin and include:

  • rash,
  • itching,
  • hives,
  • abnormal hair loss, and
  • skin pigmentation.

Pregnancy and Methimazole

Studies show that methimazole may cause birth defects.

Manufacturers of the drug state that it's not safe to take during pregnancy.

But your doctor may feel that the benefits of taking the drug during pregnancy outweigh the risks in certain situations.

Methimazole is passed into breast milk, and its safety for nursing babies has been a topic of debate. Talk to your doctor before taking the drug while breastfeeding.

It's always a good idea to talk to your doctor about all medications you're taking if you're pregnant, planning a pregnancy, or breastfeeding.


This medication contains methimazole. Do not take Northyx or Tapazole if you are allergic to methimazole or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.