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Metformin Hcl 1000 Mg Side Effects Introduction

Metformin Hcl 1000 Mg Side Effects

Introduction

Metformin is a prescription drug used to treat type 2 diabetes. It belongs to a class of medications called biguanides. People with type 2 diabetes have blood sugar (glucose) levels that rise higher than normal. Metformin doesn’t cure diabetes. Instead, it helps lower your blood sugar levels to a safe range.

Metformin needs to be taken long-term. This may make you wonder what side effects it can cause. Metformin can cause mild and serious side effects, which are the same in men and women. Here’s what you need to know about these side effects and when you should call your doctor.

Dosage

The usual starting dose of metformin hydrochloride tablets is 500 mg twice a day or 850 mg once a day, given with meals. Dosage increases should be made in increments of 500 mg weekly or 850 mg every 2 weeks, up to a total of 2000 mg per day, given in divided doses. Patients can also be titrated from 500 mg twice a day to 850 mg twice a day after 2 weeks. For those patients requiring additional glycemic control, metformin hydrochloride tablets may be given to a maximum daily dose of 2550 mg per day. Doses above 2000 mg may be better tolerated given three times a day with meals.

The usual starting dose of metformin hydrochloride extended-release tablets is 500 mg once daily with the evening meal. Dosage increases should be made in increments of 500 mg weekly, up to a maximum of 2000 mg once daily with the evening meal.

side effects of metformin

Metformin causes some common side effects. These can occur when you first start taking metformin, but usually go away over time. Tell your doctor if any of these symptoms are severe or cause a problem for you.

The more common side effects of metformin include:

  • heartburn
  • stomach pain
  • nausea or vomiting
  • bloating
  • gas
  • diarrhea
  • constipation
  • weight loss
  • headache
  • unpleasant metallic taste in mouth

Precautions

Several factors raise your risk of lactic acidosis while you take metformin. If any of these factors affect you, be sure to discuss them with your doctor before taking this drug.

Kidney problems

Your kidneys remove metformin from your body. If your kidneys don’t work well, you’ll have higher levels of metformin in your system. This raises your risk of lactic acidosis.

Heart problems

If you have acute heart failure or have recently had a heart attack, you should not take metformin. Your heart may not send enough blood to your kidneys. This would prevent your kidneys from removing metformin from your body as well as they normally would, raising your risk of lactic acidosis.

Liver problems

You should not take metformin if you have severe liver problems. Your liver clears lactic acid from your body. Therefore, severe liver problems could lead to a buildup of lactic acid. Lactic acid buildup raises your risk of lactic acidosis. Metformin also raises your risk, so taking it if you have liver problems is dangerous.

Alcohol use

Drinking alcohol while taking metformin raises your risk of hypoglycemia. It also raises your risk of lactic acidosis. This is because it increases lactic acid levels in your body.

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