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Mesalamine

Mesalamine

Uses

This medication is used to treat a certain bowel disease (ulcerative colitis). It helps to reduce symptoms of ulcerative colitis such as diarrhea, rectal bleeding, and stomach pain. Mesalamine belongs to a class of drugs known as aminosalicylates. It works by decreasing swelling in the colon.

How to use Mesalamine Capsule, Extended Release

Take this medication by mouth as directed by your doctor, usually 4 times daily. If you are taking the capsule form of this medication, you may take it with or without food. If you are taking the tablet form of this medication, take it with meals.

Swallow this medication whole. Do not crush, chew, or break. Doing so can keep the drug from being released properly into the colon. If you have trouble swallowing the capsule, you may open the capsule and sprinkle its contents on applesauce or yogurt before you take it. Swallow all of the drug/food mixture right away without chewing. Do not chew the mixture or prepare a supply in advance.

The dosage is based on your medical condition and response to treatment.

Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.            

Tell your doctor if your condition does not improve or if it worsens.

Why is this medication prescribed?

Mesalamine is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) and also to maintain improvement of ulcerative colitis symptoms. Mesalamine is in a class of medications called anti-inflammatory agents. It works by stopping the body from producing a certain substance that may cause inflammation.

Mesalamine Side Effects

Tell your doctor if any of the following side effects are severe or don't go away:

  • Headache
  • Nausea or stomach pain
  • Infection or inflammation of the nose and throat
  • Flare-ups in bowel condition

What is mesalamine?

Mesalamine affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Mesalamine is used to treat mild to moderate ulcerative colitis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.

Some brands of mesalamine are for use only in adults, and some brands are for use in children who are at least 5 years old.

Mesalamine may also be used for purposes not listed in this medication guide.

How should this medicine be used?

Mesalamine comes as a delayed-release (releases the medication in the intestine where its effects are needed) tablet, a delayed-release (releases the medication in the intestine where its effects are needed) capsule, a controlled-release (releases the medication throughout the digestive system) capsule, and as an extended-release (long-acting) capsule to take by mouth. Your doctor will tell you how often to take your medication, depending on your condition and how well your symptoms are controlled. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mesalamine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

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