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Losartan Potassium + Hydrochlorothiazide

Losartan Potassium + Hydrochlorothiazide

What is losartan/hydrochlorothiazide?

This drug is a prescription medication. It comes as an oral tablet.

This drug is available as the brand-name drug Hyzaar and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

This is a combination of two drugs in a single form. It’s important to know about all the drugs in the combination because each drug may affect you in a different way.

This drug may be used as part of a combination therapy. That means you need to take it with other drugs.


This drug is used to treat high blood pressure. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: losartan and hydrochlorothiazide. Losartan is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.

What side effects are possible with this medication?

  • abdominal pain
  • back or leg pain
  • constipation
  • cough
  • decreased appetite
  • diarrhea
  • dizziness
  • nausea
  • pins and needles sensation
  • sensitivity to the sun

Hyzaar Warnings

Before taking Hyzaar, tell your doctor if you have, or have ever had:

  • Kidney disease
  • Problems with urination
  • Liver disease
  • Congestive heart failure
  • Glaucoma
  • Asthma
  • Gout

Hyzaar Dosage

Hyzaar comes as a tablet to take by mouth. It's typically taken once or twice a day.

Your dose will depend on your medical condition and response to treatment.

Take Hyzaar with a full glass of water. It can be taken with or without food.

Follow the instructions on your prescription label carefully. Don't take more or less Hyzaar than is recommended.


Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature]. Keep container tightly closed. Protect from light