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What is levocetirizine?

Prescription levocetirizine oral tablet is available as the brand-name drug Xyzal. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

Prescription levocetirizine comes as an oral tablet and an oral solution. Both forms are also available in over-the-counter versions.

How it works

Levocetirizine belongs to a class of drugs called antihistamines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Levocetirizine works by blocking the release of a chemical called histamine from the cells in your body. This helps relieve symptoms of allergies, such as sneezing, runny nose, and red, watery, itchy eyes. This drug also helps relieve itching caused by hives.

How should I take levocetirizine?

Follow the directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

It is very important not to give a child more than the prescribed dose of this medication. A child's body absorbs twice as much of the same dose size of levocetirizine as an adult's body.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Side effects of levocetirizine?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using levocetirizine and call your doctor at once if you have:

  • painful or difficult urination
  • little or no urinating
  • signs of an ear infection (fever, ear pain or full feeling, trouble hearing, drainage from the ear, fussiness in a child)
  • a light-headed feeling, like you might pass out
  • fever
  • worsening allergy or urticaria symptoms


This medication contains levocetirizine. Do not take Xyzal Allergy 24HR Tablets, Xyzal Allergy 24HR Oral Solution, or Xyzal if you are allergic to levocetirizine or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately


  • Documented hypersensitivity
  • Lower respiratory disease, such as asthma (controversial)
  • Preemies and neonates
  • Nursing women
  • Hypersensitivity to levocetirizine or cetirizine