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L-triidotironin Sodium

L-triidotironin Sodium

Labeled Indications

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Thyroid disorders: Oral: Replacement or supplemental therapy in hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis; a diagnostic agent in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy


Tiromel T3 25 mcg (Ltriidotironin Sodium) is a prescription based drug which is also available in various substitutes and can be taken on prescription only. Consult your doctor for the duration and frequency of the medication as age and severity of the disease differ in each patient.

Patients are advised to take Tiromel T3 25 mcg at a fixed time and before the first meal of the day. It is safe to use during pregnancy or breastfeeding but dose must be optimized.


Exact mechanism of action is unknown; however, it is believed the thyroid hormone exerts its many metabolic effects through control of DNA transcription and protein synthesis; involved in normal metabolism, growth, and development; promotes gluconeogenesis, increases utilization and mobilization of glycogen stores, and stimulates protein synthesis, increases basal metabolic rate.


Hypersensitivity to liothyronine sodium or any component of the formulation; undocumented or uncorrected adrenal insufficiency; untreated thyrotoxicosis; artificial rewarming (injection)


Canadian labeling: Additional contraindications (not in the US labeling): Acute myocardial infarction.


Do not stop taking Tiromel T3 25 mcg on your own in between the course or do not take it for longer than recommended by your doctor.


Store the Tiromel T3 25 mcg tablet at cool temperature away from sunlight in clean and dry place. Make sure that tablets bottle is not damaged or destroyed while purchasing and storing.