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About Ivabradine

Ivabradine, marketed under the trade name Corlanor among others,is a medication used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

Ivabradine acts by reducing the heart rate via specific inhibition of the pacemaker current, a mechanism different from that of beta blockers and calcium channel blockers, two commonly prescribed antianginal drugs. Ivabradine is a cardiotonic agent.

Side effects can this medication cause?

Some side effects can be serious. If you experience any of these symptoms call your doctor immediately or get emergency medical treatment:

  • fast, irregular, or pounding heartbeat
  • slow or stopped heartbeat
  • chest pain or pressure
  • worsening shortness of breath
  • dizziness
  • excessive tiredness
  • lack of energy

Drug Interactions

Advise patient to avoid ingestion of grapefruit juice and St.John's wort [see DRUG INTERACTIONS].

Intake With Food

Advise patient to take Corlanor twice daily with meals


Overdose may lead to severe and prolonged bradycrdia. In the event of bradycardia with poor hemodynamic tolerance, temporary cardiac pacing may be requied. Supportive treatment, including intravenous(IV)fluids, atropine and intravenous beta-stimulating agents such as isoproterenol,may be considered.

Dosage Forms & Strengths


  • 5mg
  • 7.5mg

Storage And Handling

Corlanor 5 mg tablets are formulated as salmon-colored, oval-shaped, film-coated tablets scored on both edges, marked with “5” on one face and bisected on the other face. They are supplied as follows:

Bottles of 60 tablets (NDC 55513-800-60)

Bottles of 180 tablets (NDC 55513-800-80)