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Itraconazole For Cats

itraconazole for cats

How Is Itraconazole Administered?

Itraconazole is most commonly prescribed in the form of an oral capsule, but other formulations are available, including oral suspension, ophthalmic solution and topical applications. The mode with which this drug is administered is determined by the treating veterinarian, along with dosage and frequency.

Since Itraconazole fights a fungal infection, it is very important to finish the course of treatment even if the patient is looking, acting or feeling better. Fungal infections are more resilient than bacterial infections and usually require a longer course of therapy. Failure to complete the entire prescription may increase the risk of a relapse.

Itraconazole Precautions

Itraconazole is generally safe and effective when used in accordance with veterinary directions. It should not, however, be prescribed to an animal that has exhibited signs of an allergic reaction or hypersensitivity to it previously.

In rare cases, itraconazole may affect the function of the liver. Therefore, it is recommended to watch for signs of jaundice when the animal is taking this medication. The veterinarian may also want to perform routine liver tests if a patient receives this medication long-term.

Drug Interactions

Be sure to review with your veterinarian any medications or supplements your pet may be receiving.

Antacids or drugs that decrease stomach acid, such as omeprazole, ranitidine or cimetidine will decrease the amount of Itraconazole that is absorbed. Always give itraconazole and these medication two hours apart.

There are a number of drugs that may interact with itraconazole. They include: didanosine, warfarin or other coumarin anticoagulants; rifampin, phenytoin, cyclosporine, digoxin, chlorpropamide, glipizide, and cisapride.

How Is Itraconazole Administered?

Itraconazole is most commonly prescribed in the form of an oral capsule, but other formulations are available, including oral suspension, ophthalmic solution and topical applications. The mode with which this drug is administered is determined by the treating veterinarian, along with dosage and frequency.

Since Itraconazole fights a fungal infection, it is very important to finish the course of treatment even if the patient is looking, acting or feeling better. Fungal infections are more resilient than bacterial infections and usually require a longer course of therapy. Failure to complete the entire prescription may increase the risk of a relapse.

Precautions and Side Effects

While generally safe and effective when prescribed by a veterinarian, itraconazole can cause side effects in some animals.

Itraconazole should not be used in animals with known hypersensitivity or allergy to the drug.

Itraconazole should not be used in pregnant or nursing dogs or cats.

The most serious adverse effect is that which affects the liver (hepatitis). Signs of decreased appetite, jaundice, vomiting or diarrhea should be reported to your veterinarian.

Itraconazole may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with itraconazole. Such drugs include antacids, digoxin, cisapride, amphotericin B, various sedative such as diazepam,  alprazolam and midazolam), buspirone, corticosteroids, ranitidine, famotidine, omeprazole, ivermectin, phenobarbital, vincristine, vinblastine, clomipramine, amitriptyline, and certain antibiotics.

Compared to some of the other antifungal drugs (amphotericin B, ketoconazole), itraconazole has been associated with fewer adverse effects.

Itraconazole may cause vomiting, diarrhea, weight loss, depression, and decreased appetite in dogs and cats.

Storage

Different strengths or dosage forms of itraconazole may have different storage requirements. Read the labeling or ask your pharmacist for the storage requirements of the prescription you receive.

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