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Itraconazole Cost

itraconazole cost

Uses of Itraconazole 100mg

Itraconazole Is An Antifungal Medicines And Is Used In The Treatment Of Various Fungal Or Yeast Infection. Itraconazole Primarily Used In The Treatment Of Fungal Infection Of Toes, Nails, Skin , Esophaghus And Mouth .

Mechanism of Action of Itraconazole 100mg

Itraconazole Decreases Ergosterol Biosynthesis By Interfering With Cytochrome P450 Activity. This Inhibits Cell Membrane Function Of Susceptible Fungi Including Microsporum Species, Trichophyton Species, Candida Species, Cryptococcus Neoformans, Histoplasma Capsulatum, Blastomyces Dermatitidis And Paracoccidiodes Brasiliensis. It Also Has Antiprotozoal Activity Against Leishmania Major. Absorption: Absorbed From The GIT, Capsule Enhanced By Acidic Gastric Environment Or When Taken With Food; Oral Liquid Better Absorbed During Fasting State. Peak Plasma Concentrations Are Achieved After 1.5-5 Hr. Distribution: Itraconazole Is Extensively Bound (99.8%) To Plasma Protein. Widely Distributed In Skin, Sebum, Pus And Other Tissues And Organs (Higher Concentrations Compared To Plasma). Small Amounts Are Distributed In CSF And Breast Milk. Metabolism: Undergoes Saturable Hepatic Metabolism (Via Cytochrome P450 Isoenzyme CYP3A4); Converted To Hydroxyitraconazole (Antifungal Activity Comparable To The Parent Drug) And Other Metabolites. Excretion: Via Urine Or Bile (As Inactive Metabolites), Via Faeces (3-18% As Unchanged), Stratum Corneum And Hair (Small Amounts);

Why is this medication prescribed?

Itraconazole capsules are used to treat fungal infections in the lungs that can spread throughout the body. Itraconazole capsules are also used to treat fungal infections of the fingernails. Itraconazole tablets and capsules are used to treat fungal infections of the toenails. Itraconazole oral solution (liquid) is used to treat yeast infections of the mouth and throat or of the esophagus (tube that connects the throat to the stomach). Itraconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection.

How should this medicine be used?

Itraconazole comes as a capsule, a tablet, and a solution (liquid) to take by mouth. If you are taking itraconazole to treat fungal infections in the lungs, the capsules are usually taken during or right after a full meal one or two times a day for at least 3 months. However, if you are taking itraconazole to treat a serious fungal infection in the lungs, the capsules may be taken with a meal three times a day for the first 3 days of treatment and then taken once or twice a day with a meal for at least 3 months. If you are taking itraconazole to treat fungal infections of the toenails (including or without fingernail infections), the capsules or tablets are usually taken once a day with a full meal for 12 weeks. If you are taking itraconazole to treat fungal infections of the fingernails only, the capsules are usually taken twice a day with a full meal for 1 week, skipped for 3 weeks, and then taken twice a day with a meal for a week. Itraconazole oral solution is usually taken on an empty stomach once or twice a day for 1 to 4 weeks or sometimes longer. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take itraconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow itraconazole capsules whole; do not open, chew, or crush them.

Warnings and Precautions for Canditral

Caution should be exercised in patients with history of HIV infection, weakened immune system, kidney or liver problems, abnormal liver function tests, lung or breathing problems, irregular heartbeat, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

It may affect blood sugar level; monitor sugar level regularly while taking this medication.

Storage Conditions for Canditral

Store it at room temperature and in an airtight container.

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