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Isoxsuprine Hcl

Isoxsuprine Hcl

Informaton of Isoxsuprine Hcl

Isoxsuprine hydrochloride is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

Isoxsuprine Dosage

Take isoxsuprine exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Isoxsuprine dose your doctor recommends will be based on the following (use any or all that apply):

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height

Side Effects

Side effects after oral administration are rare in the horse because of the low level of absorption. Possible side effects could include low blood pressure, increased heart rate, and possible gastrointestinal irritation.

Side effects after intravenous administration include hypotension, tachycardia, CNS stimulation, and sweating.

Isoxsuprine Interactions

This is not a complete list of Isoxsuprinedrug interactions. Ask your doctor or pharmacist for more information.


Isoxsuprine is a vasodilator and should not be used in mares immediately after foaling or horses that are actively bleeding.

Despite the low level of oral absorption, isoxsuprine can be found in a horse’s urine for many weeks after treatment is discontinued. This may be a consideration for competition horses.

There are no safety studies on isoxsuprine use in pregnant or lactating mares. There are no safety studies regarding the effects on semen in breeding stallions.

Drug Interactions

Drug interactions are unlikely with oral isoxsuprine.

Warnings for special population

Pregnancy - This medicine is not recommended for pregnant women unless necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.

Breast-feeding - The excretion of this medicine in breast milk is unknown. It is not recommended in pregnant women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.


 Tablets should be stored in tight containers at room temperature (15-30°C).